ID A0A0D2JS36_9EURO Unreviewed; 531 AA.
AC A0A0D2JS36;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
GN ORFNames=Z520_11104 {ECO:0000313|EMBL:KIX93249.1};
OS Fonsecaea multimorphosa CBS 102226.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442371 {ECO:0000313|EMBL:KIX93249.1, ECO:0000313|Proteomes:UP000053411};
RN [1] {ECO:0000313|EMBL:KIX93249.1, ECO:0000313|Proteomes:UP000053411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 102226 {ECO:0000313|EMBL:KIX93249.1,
RC ECO:0000313|Proteomes:UP000053411};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea multimorphosa CBS 102226.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC {ECO:0000256|RuleBase:RU004453}.
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DR EMBL; KN848096; KIX93249.1; -; Genomic_DNA.
DR RefSeq; XP_016627372.1; XM_016781594.1.
DR AlphaFoldDB; A0A0D2JS36; -.
DR STRING; 1442371.A0A0D2JS36; -.
DR GeneID; 27716850; -.
DR VEuPathDB; FungiDB:Z520_11104; -.
DR OrthoDB; 360175at2759; -.
DR Proteomes; UP000053411; Unassembled WGS sequence.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR45708; ENDOCHITINASE; 1.
DR PANTHER; PTHR45708:SF49; ENDOCHITINASE; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000053411};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..531
FT /note="chitinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002245124"
FT DOMAIN 180..531
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
SQ SEQUENCE 531 AA; 56513 MW; D08F96DD2B1124F0 CRC64;
MAFYDRFVLF LCLTLCTYSV LASTPTGDWK GIAASLRSTL DAIELSHAQH LPRSGGSRSR
RDAIFRAGPS GYWRPLAPSQ RPNSSEDFSE QLDQLVGEIG SAVEQLIELL ASEFNFGTLS
TTLPTPPQTT IFPITDINTT PSGSTILTSY ATSSPINTAP FTSSIPSPTA TSTFNPQAPD
LNVVYYSQTD LTPVISLAQI CNDPAVDVVI LAFVTSLISN GGYPAMNMAS NCWAPHAAQQ
AAGATGLLDC VGDGFSSMIA TCQQQGKKVL LSLGGSVGTL TMSSQDQAVE VANTLWSLFL
GGSNATLAPL RPYGNIVLDG IDIDNELPSA ATYIPTLVST LRQLMGSDSS KSYYLSAAPQ
CPRPDASIPV ASLLNYIDFF SVQFYNNPSC QLSSGQGFFD SLQAWSADLQ ALNDTLSSTR
RNKRSSRGGA VLRIRQEASP DNTFYNINNG ITSPRLLIGT PAFPAAGSGY VDVATYKSIL
EQVKNMSLPN LAGAMFWDGA YQEVSAQEVP DGDGGSQNVT FAQVVREVLA Q
//
