ID A0A0D2M579_GOSRA Unreviewed; 629 AA.
AC A0A0D2M579;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS01186};
GN ORFNames=B456_002G010300 {ECO:0000313|EMBL:KJB12292.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB12292.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB12292.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00029430}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00029430}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004614}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004614}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}. Prevacuolar compartment membrane
CC {ECO:0000256|ARBA:ARBA00043947}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00043947}.
CC -!- SIMILARITY: Belongs to the VSR (BP-80) family.
CC {ECO:0000256|ARBA:ARBA00007038}.
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DR EMBL; CM001741; KJB12292.1; -; Genomic_DNA.
DR EMBL; CM001741; KJB12293.1; -; Genomic_DNA.
DR RefSeq; XP_012450825.1; XM_012595371.1.
DR RefSeq; XP_012450832.1; XM_012595378.1.
DR AlphaFoldDB; A0A0D2M579; -.
DR STRING; 29730.A0A0D2M579; -.
DR EnsemblPlants; KJB12292; KJB12292; B456_002G010300.
DR EnsemblPlants; KJB12293; KJB12293; B456_002G010300.
DR GeneID; 105773445; -.
DR Gramene; KJB12292; KJB12292; B456_002G010300.
DR Gramene; KJB12293; KJB12293; B456_002G010300.
DR KEGG; gra:105773445; -.
DR eggNOG; ENOG502QSX2; Eukaryota.
DR OrthoDB; 305396at2759; -.
DR Proteomes; UP000032304; Chromosome 2.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd02125; PA_VSR; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR PANTHER; PTHR22702; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22702:SF1; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF02225; PA; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..629
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007395245"
FT TRANSMEM 570..592
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 502..516
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
SQ SEQUENCE 629 AA; 69530 MW; E11010996CDAD36F CRC64;
MELRTFHHHL LQGFMLLSFI SNCCARFVVE KNSLTVTSPE KIKGTHDSAI GNFGIPQYGG
SMAGVVVYPK ENQKACKSFG DFGISFKSKP GSLPTFVLVD RGDCFFALKV WNVQQAGASA
VLVADDIEEA LITMDNPEED SSSAKYIENI TIPSALIEKT FGETLKKAIS GGDMVNVNLD
WREAVPHPDD RVEYELWTNS NDECGVKCDM LMAFVKDFKG AAQILEKGGY TQFTPHYITW
YCPQAFTLSR QCKSQCINRG RYCAPDPEQD FSSGYEGKDV VIENLRQLCV FKVANETNRP
WVWWDYVTDF QIRCPMKEKK YNKECADVVI KSLGLDAKKI EKCMGDPDAD MENPVLKEEQ
DAQVGKGSRG DVTILPTLVV NNRQYRGKLA KGAVLKAICA GFEETTEPAV CLSGDVETNE
CLENNGGCWQ DKAANLTACR DTFRGRVCEC PLVDGVQFKG DGYSHCEPGG PGRCKINNGG
CWHESQNGSA YSACLDNGDV KCQCPPGFKG DGVKSCEDID ECKEKRACQC PECSCKNTWG
SYECTCNGDL LYIRDHDTCI SKSGTEVRSA WAAMSVILIG LAMAGGGAYL VYKYRLRSYM
DSEIRAIMAQ YMPLDSQGEV PNHVSNDRA
//
