ID A0A0D2MCI4_GOSRA Unreviewed; 637 AA.
AC A0A0D2MCI4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Auxin efflux carrier component {ECO:0000256|RuleBase:RU362108};
GN ORFNames=B456_002G179000 {ECO:0000313|EMBL:KJB15457.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB15457.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB15457.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- FUNCTION: May act as a component of the auxin efflux carrier.
CC {ECO:0000256|RuleBase:RU362108}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362108}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362108}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC {ECO:0000256|ARBA:ARBA00009177, ECO:0000256|RuleBase:RU362108}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362108}.
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DR EMBL; CM001741; KJB15457.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2MCI4; -.
DR EnsemblPlants; KJB15457; KJB15457; B456_002G179000.
DR Gramene; KJB15457; KJB15457; B456_002G179000.
DR Proteomes; UP000032304; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0060918; P:auxin transport; IEA:UniProt.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-UniRule.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR014024; Auxin_eff_plant.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR NCBIfam; TIGR00946; 2a69; 1.
DR PANTHER; PTHR31752; AUXIN EFFLUX CARRIER COMPONENT 1B-RELATED; 1.
DR PANTHER; PTHR31752:SF18; AUXIN EFFLUX CARRIER COMPONENT 4; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294,
KW ECO:0000256|RuleBase:RU362108};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362108};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362108};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362108}; Transport {ECO:0000256|RuleBase:RU362108}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 524..543
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 555..577
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 583..603
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 610..634
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT REGION 280..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 69531 MW; 7C85C93CBFBC9358 CRC64;
MISWNDLYTV LTAVIPLYVA MILAYGSVRW WKIFTPDQCS GINRFVAIFA VPLLSFHFIS
TNDPYAMNFR FIAADTLQKL IMLFALGLWT NLTRNGSLEW MITIFSLSTL PNTLVMGIPL
LIAMYGPYSG MLMVQVVVLQ CIIWYTLLLF LFEYRGAKIL IMEQFPETAA SIVSFKVDSD
VVSLDGRDFL ETDAEIGEDG KLHVKVRKSN ASRRSLGPCS LPALTPRPSN LTGAEIYSLS
SSRNPTPRGS NFNNSDFYSM MGVQGFPARH SNFGPADLYS VQSSRGPTPR PSNFEENNTV
MSPRFGFYPA QTVPSSYPAP NPEFSSVTKN AKATQQQQQQ PEKENNKENH DAKELHMFVW
SSSASPVSEG GGLHVFGGTD FGVSEQSGRS EQGAKEIRML VADHPQNGEN KGMAGSGDVN
GEDFSFAGRD GEEEREKEGP NGLNKLGSSS TAELHPKAAG GPESGVGKQM PPASVMTRLI
LIMVWRKLIR NPNTYSSLIG LVWSLIAFRW HVSMPKIIEK SISILSDAGL GMAMFSLGLF
MALQPKIIAC GNSVATFAMA VRFLTGPAVM AAASIAVGLR GTLLRVAIVQ AALPQGIVPF
VFAKEYNVHP AILSTAVIFG MLIALPITLV YYILLGL
//
