GenomeNet

Database: UniProt
Entry: A0A0D2PZZ4_GOSRA
LinkDB: A0A0D2PZZ4_GOSRA
Original site: A0A0D2PZZ4_GOSRA 
ID   A0A0D2PZZ4_GOSRA        Unreviewed;       605 AA.
AC   A0A0D2PZZ4;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   28-FEB-2018, entry version 12.
DE   RecName: Full=Malic enzyme {ECO:0000256|RuleBase:RU003426};
GN   ORFNames=B456_001G170700 {ECO:0000313|EMBL:KJB09851.1};
OS   Gossypium raimondii (New World cotton).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae;
OC   Gossypium.
OX   NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB09851.1, ECO:0000313|Proteomes:UP000032304};
RN   [1] {ECO:0000313|EMBL:KJB09851.1, ECO:0000313|Proteomes:UP000032304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23257886; DOI=10.1038/nature11798;
RA   Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA   Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA   Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J.,
RA   Grover C., Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T.,
RA   Marler B.S., Page J.T., Roberts A.W., Romanel E., Sanders W.S.,
RA   Szadkowski E., Tan X., Tang H., Xu C., Wang J., Wang Z., Zhang D.,
RA   Zhang L., Ashrafi H., Bedon F., Bowers J.E., Brubaker C.L., Chee P.W.,
RA   Das S., Gingle A.R., Haigler C.H., Harker D., Hoffmann L.V., Hovav R.,
RA   Jones D.C., Lemke C., Mansoor S., ur Rahman M., Rainville L.N.,
RA   Rambani A., Reddy U.K., Rong J.K., Saranga Y., Scheffler B.E.,
RA   Scheffler J.A., Stelly D.M., Triplett B.A., Van Deynze A.,
RA   Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J., Zaki E.A.,
RA   Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA   Wang X., Schmutz J.;
RT   "Repeated polyploidization of Gossypium genomes and the evolution of
RT   spinnable cotton fibres.";
RL   Nature 492:423-427(2012).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000106-3};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000106-3};
CC       Note=Divalent metal cations. Prefers magnesium or manganese.
CC       {ECO:0000256|PIRSR:PIRSR000106-3};
CC   -!- SIMILARITY: Belongs to the malic enzymes family.
CC       {ECO:0000256|RuleBase:RU003426}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CM001740; KJB09851.1; -; Genomic_DNA.
DR   EnsemblPlants; KJB09851; KJB09851; B456_001G170700.
DR   Gramene; KJB09851; KJB09851; B456_001G170700.
DR   Proteomes; UP000032304; Chromosome 1.
DR   GO; GO:0004471; F:malate dehydrogenase (decarboxylating) (NAD+) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.50.10380; -; 1.
DR   InterPro; IPR015884; Malic_enzyme_CS.
DR   InterPro; IPR012301; Malic_N_dom.
DR   InterPro; IPR037062; Malic_N_dom_sf.
DR   InterPro; IPR012302; Malic_NAD-bd.
DR   InterPro; IPR001891; Malic_OxRdtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00390; malic; 1.
DR   Pfam; PF03949; Malic_M; 1.
DR   PIRSF; PIRSF000106; ME; 1.
DR   PRINTS; PR00072; MALOXRDTASE.
DR   SMART; SM01274; malic; 1.
DR   SMART; SM00919; Malic_M; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00331; MALIC_ENZYMES; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000032304};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000106-3,
KW   ECO:0000256|RuleBase:RU003426};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003426};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT   DOMAIN      107    287       malic. {ECO:0000259|SMART:SM01274}.
FT   DOMAIN      297    561       Malic_M. {ECO:0000259|SMART:SM00919}.
FT   ACT_SITE    130    130       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR000106-1}.
FT   ACT_SITE    201    201       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000106-1}.
FT   METAL       272    272       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000106-3}.
FT   METAL       273    273       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000106-3}.
FT   METAL       296    296       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR000106-3}.
SQ   SEQUENCE   605 AA;  66984 MW;  AFD184D64FF3D0F0 CRC64;
     MWNLTRFASS RLSRTRRLFS SVIPGPCIVH KRGTDILHDP WFNKDTGFPL TERDRLGLRG
     LLPPRVISFE QQYDRFMESY HSLEKNTKGQ PDGVVALAKW RILNRLHDRN ETLYYRVLMD
     NIKDFAPIIY TPTVGLVCQN YSGLFRRPRG MYFSAKDKGE MMSMIYNWPA QHVDMIVLTD
     GSRILGLGDL GVQGIGIPIG KLDMYVAAAG INPQRVLPVM LDVGTNNQKL LEDRLYLGLR
     QPRLEGEEYL EIVDEFMEAV FTRWPKAIVQ FEDFQMKWAF ETLDRYRKKF CMFNDDIQGT
     AGVALAGLLG TVRAQGRTLA DFPDQKIVVV GAGSAGLGVL SMAVQAVARM TGKNETAAQN
     FFLLDKDGLI TKERKNLDPA AAPFAKDPGQ IVGLREGASL LEVVKKVKPD VLLGLSGVGG
     VFSEEVEVLK ALRESGSTRP AIFAMSNPTM NAECTAADAF KHAGENIVFA SGSPFENVNL
     GNGKVGYVNQ ANNMYLFPGI GLGSLVSGAR FITDGMLQAA AECLASYMTD EEIQKGILYP
     SIDSIRHITA EVGASVLRAA VAEEVAEGHG DVGPKELAHM SKEETVEYVF RNMWYPIYSP
     LVQEK
//
DBGET integrated database retrieval system