ID   A0A0D2U0E2_CAPO3        Unreviewed;      1117 AA.
AC   A0A0D2U0E2;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=alpha-mannosidase {ECO:0000256|ARBA:ARBA00012752};
DE            EC=3.2.1.24 {ECO:0000256|ARBA:ARBA00012752};
GN   ORFNames=CAOG_000287 {ECO:0000313|EMBL:KJE88681.1};
OS   Capsaspora owczarzaki (strain ATCC 30864).
OC   Eukaryota; Filasterea; Capsaspora.
OX   NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE88681.1, ECO:0000313|Proteomes:UP000008743};
RN   [1] {ECO:0000313|Proteomes:UP000008743}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; KE346360; KJE88681.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D2U0E2; -.
DR   STRING; 595528.A0A0D2U0E2; -.
DR   EnsemblProtists; KJE88681; KJE88681; CAOG_000287.
DR   eggNOG; KOG4342; Eukaryota.
DR   InParanoid; A0A0D2U0E2; -.
DR   PhylomeDB; A0A0D2U0E2; -.
DR   Proteomes; UP000008743; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10813; GH38N_AMII_Man2C1; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008743}.
FT   DOMAIN          601..681
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1117 AA;  125011 MW;  3E0E6914BCA1F7A3 CRC64;
     MDGDAKVRFF KLVTMLTKPP VAYETGRGAR QLHKVFVRVC TMEVCHGWYP GSRRCLNRND
     QALDTTARQP PPPQKHTNVT IERVEKLLSG IYFTDANLGH PHLVYGGDLP CATRQPFAHL
     LHRPATGTSR PTFAQVLSDG DGGFTRVERT KSFGPSWTTH WFAFDLVIPP AWAGREVHFR
     WNSNSEALIY DEHGEPRQGL TGGDGCDVRS EYIVTRSARE GGETRRIYVE MAANGMFGVG
     DNGLINPPNE NRFFDISLCE LAVFDRELWL LIQDVRTLYD LSKTFADNSP RKLQAALSAN
     KIANLIDPRD RSTYPAARTV AAAFFSQRNG DSQHSISAIG HCHIDTAWLW PYDETIRKCA
     RSFATVDRYM DDYPELKFAC SQAQQLDWIR LYYPGLFSRL RERVKQGRFI PVGGAWQDGN
     IPSGEAMARQ FLYGQTFFQR EFGITCKEFW LPDTFGYSAQ LPQLMRQAGI SRFVTQKLSW
     NLINKFPHNT FHWEGIDGSR VLTHFPPADT YNSQVLPDEV MKSITNFKDH GRSRESMMLF
     GHGDGGGGPQ MVMLERMRRM QDCDGVPKIN VRSPDEFFTR VEAEMAQEDQ LLTWVGELYL
     ELHRGTYTSQ ANNKKGNRKG ELLLRNVEML VSIVQALNLP GPAEAKSELD RLWKLLLLNQ
     FHDVLPGSSI AMVYRDSDRH YADITASGNS LLQTALSTLS SSSKTSNESL VVMNTLSWER
     TSVVQTADGG FGNDLRLVTV PAIGTSLVPS ESIQDISAPV VAQKTDSNTW ILENNVLRAE
     FNAQGALISL IQSETGREAI ARGGDGGNRF VLFDDIPLFW DAWDMQEYHL EKSHLVHSDA
     GVVVRPTVSP LVGELEFTIP ISARSTIRQT VRLTHGQRFV EFATQVDWHE ARKCLKVEFP
     MNVRTSLATY DIQFGFVQRP THTNTSWDMA KFEVCGHRYG DLSEHGFGIA LLNDCKYGYS
     ARGNVMRLSL LRAPKAPDAE CDMGLHTFTY AIMPHQGSFQ EGGVVRAAAE LNSPLLVVPG
     HAQSRSFFSL LPASTSVVIE AIKPAESAPK KLVLRLFESY GGQARVTLAS TLPIASVQLS
     NIIEVDSGSP LDWNQATGVT LTFHAFEVKT LLVTLQE
//