ID A0A0D2UBU3_GOSRA Unreviewed; 857 AA.
AC A0A0D2UBU3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_008G292000 {ECO:0000313|EMBL:KJB53075.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB53075.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB53075.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
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DR EMBL; CM001747; KJB53075.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2UBU3; -.
DR STRING; 29730.A0A0D2UBU3; -.
DR EnsemblPlants; KJB53075; KJB53075; B456_008G292000.
DR Gramene; KJB53075; KJB53075; B456_008G292000.
DR eggNOG; KOG0082; Eukaryota.
DR Proteomes; UP000032304; Chromosome 8.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR PANTHER; PTHR10218:SF317; EXTRA-LARGE GUANINE NUCLEOTIDE-BINDING PROTEIN 3-LIKE; 1.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REGION 44..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..159
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 98044 MW; 4D34A4D6035D4B3A CRC64;
MAAKEAEEEN RAWEDVIRRM LPVGAPLPDE DHLDYSIAIE YEGPPIPYDV PRVDPLDLDS
LSASDISSIP FKKNRYAVRN GSPLESQRPS SASRSQIDSR NGDYDSEIEV DKSPPPPPPE
QSQQQHPDKK NVVVTFNTPK DSETDDGEAE EEDDDDDGYT SSQSSVAGRG ALLENVETRG
IVKQKKRGIC SRCGKRSRLK EREACLVCDA RYCNNCLLKA MGSMPEGRKC VSCIKKPIDE
AKRSRLGKSS RLLRKVCSPL EVQQIMKAEK ECAANQLRPE QLVVNGRQLN HEELAELFGC
PVPPQKLKPG RYWYDKDSGF WGKEGEKPDS IISSKLNIGS KLKKDASNGN TRVFINGREI
TKTELRVLKL AKVQCPRDTH FWVYEDGSYE EEGQNNIKGK IWEKAFTRFC CSLFSLPVPP
TNPHGPQEDP TTFSGRSVPE YLGHGRVQKL LLFGLEGSGT STIFKQAKFL YGNGFSPEEM
ENIKHMIQSN MYKYLSVLLE GRERFEEEAL SELRTNNLDA EKSDSDETGI DGSNQCIYSI
NPRFKHFSDW LLDIVAMGDF DKFFPAATRE YARTVDELWK DPAIQETCKR IEELHHLPDV
AKYFLERAVE ISSNEYEPSE KDILYAEGVT QSNGLASLEF SFDDRSPMSE IYDNNFECSP
SLTKYQLIRI NSKGLHDGCK WLAMFEDVRA VIFCVALTDY DEMWSRGTGP IYNKMLASRD
MFENLVRHPS FKEIPFVLLL TKYDALENKI NRTPLSTCEW FKDFSPLRPH HNHHALAQQA
YYYVAVKFKE LYSSICGQKL FVWQTKGRER RSIDEAFKYI REVLKWDEEK NENMYEIHGD
DSFYSTEMSS SPYIRQE
//
