ID A0A0D3AVI5_BRAOL Unreviewed; 309 AA.
AC A0A0D3AVI5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00012526};
DE EC=2.7.7.60 {ECO:0000256|ARBA:ARBA00012526};
GN Name=106327327 {ECO:0000313|EnsemblPlants:Bo2g136340.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo2g136340.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo2g136340.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo2g136340.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- PATHWAY: Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis
CC via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-
CC phosphate: step 2/6. {ECO:0000256|ARBA:ARBA00004787}.
CC -!- SIMILARITY: Belongs to the IspD/TarI cytidylyltransferase family. IspD
CC subfamily. {ECO:0000256|ARBA:ARBA00009789}.
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DR RefSeq; XP_013620908.1; XM_013765454.1.
DR RefSeq; XP_013620909.1; XM_013765455.1.
DR AlphaFoldDB; A0A0D3AVI5; -.
DR STRING; 109376.A0A0D3AVI5; -.
DR EnsemblPlants; Bo2g136340.1; Bo2g136340.1; Bo2g136340.
DR GeneID; 106327327; -.
DR Gramene; Bo2g136340.1; Bo2g136340.1; Bo2g136340.
DR KEGG; boe:106327327; -.
DR eggNOG; ENOG502QUUE; Eukaryota.
DR HOGENOM; CLU_061281_0_0_1; -.
DR OMA; TPMLIHA; -.
DR OrthoDB; 1214813at2759; -.
DR UniPathway; UPA00056; UER00093.
DR Proteomes; UP000032141; Chromosome C2.
DR GO; GO:0050518; F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0019288; P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; IEA:UniProtKB-UniPathway.
DR CDD; cd02516; CDP-ME_synthetase; 1.
DR HAMAP; MF_00108; IspD; 1.
DR InterPro; IPR001228; IspD.
DR InterPro; IPR034683; IspD/TarI.
DR InterPro; IPR018294; ISPD_synthase_CS.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR00453; ispD; 1.
DR PANTHER; PTHR32125; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR32125:SF4; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR Pfam; PF01128; IspD; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS01295; ISPD; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 309 AA; 34576 MW; F543DE92A22B4CC9 CRC64;
MAMLQTTLGF LNSPTFSFSS SYFCPNLSVK STSLCLGFSC RPSVQILDFS KRVSRSYRRD
AFIHSVRCSS SSEFDNSNAV VKEKSVSVIL LAGGQGKRMK MTMPKQYIPL LGQPIALYSF
FTFSRMSEVK EIVVVCDPFF RDIFEEYEES IDVDLKFAVP GKERQDSVHS GLQEIDANAE
LVCIHDSARP LVDTEDVEKV LKDGWTVGAA VLGVPAKATI KEVNADSLVV KTLDRKTLWE
MQTPQVIKPE LLKRGFELVK REGLEVTDDV SIVEYLKHPV YVTQGSYTNI KVTTPDDLLL
AERILSMDS
//
