ID A0A0D3BA15_BRAOL Unreviewed; 1232 AA.
AC A0A0D3BA15;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN Name=106332440 {ECO:0000313|EnsemblPlants:Bo3g060780.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo3g060780.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo3g060780.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo3g060780.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
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DR RefSeq; XP_013626353.1; XM_013770899.1.
DR AlphaFoldDB; A0A0D3BA15; -.
DR STRING; 109376.A0A0D3BA15; -.
DR EnsemblPlants; Bo3g060780.1; Bo3g060780.1; Bo3g060780.
DR GeneID; 106332440; -.
DR Gramene; Bo3g060780.1; Bo3g060780.1; Bo3g060780.
DR KEGG; boe:106332440; -.
DR eggNOG; ENOG502SUNR; Eukaryota.
DR HOGENOM; CLU_001561_0_1_1; -.
DR OMA; DFTHTAF; -.
DR OrthoDB; 659721at2759; -.
DR Proteomes; UP000032141; Chromosome C3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11017:SF482; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..226
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1176..1214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1176..1191
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1192..1206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1232 AA; 139536 MW; 6A913FF44DA351E1 CRC64;
MDSPSLYPAI GFLTLLVTTF LMAYRRYKLH QNKDLIASSL SPSPRSSSLS PSSLPSSVSR
NWRHQVFPSF RGEDVRRGFL SHIQKEIERK GITLFIDNDI DRSKSIGPEL IEAIRRSKIS
VVLISKNYAS STWCLNELVE IIKCRKELDQ IVMIIFYEVD PSDVKKQSGE FGNVFEKTCV
GKTVEDVARW REALEEVAKI AGYDSRSWNN EADMIEKVAK DVSNMLNVAA PSSGLDELVG
IESHITEISS VLSLASDEVR MVGIWGPAGI GKTTIARTLF SIISHDFTHT AFVESTKRGY
NDDTAFKLHL QEQLLSKTLD HKDLKIDHLG VAEARLKDKK VLVVLDDVEE AMQLQAMACK
TQWFGCGSRI IITTKDIKVL KAHGINHVYH VGYPRWSEAL EILCLSAFGQ KSPYAGFEEL
TMEVVSLAGK LPLGLSVFGS YMRGMSKDEW THALPRLRTS LDGNIEKVLR LSYDALCDKD
KTLFLHIACF FKHEKAKDML ECLEESDLDV KHGLQVLTER SLVSINRVDY LLMHSLLQQM
GKEIIGKEDI NEPKRRRFLM DAHGICDVLS DTTVSGAVLG IDLDINAVKE ELSLDERAFE
GMSRLQFLRV YNDNKLILPR GLNNLPRKLR LLHWYRFPMS FLPCEFRAEF LVNLKMQHSH
LEKLWEGTPA PLRCLKRMDL SYSYHLRKVP DLSNATNLEA LILTGCRNLE ELPSSVNNLE
SLVELRLKGC PTPKDLSAKI SLWKSPSQIQ VFECSGLRVL RDVDTTGVTL SLYCDTKIKK
MPSWIKLLSH LHTIALTKCH SLKVFPRVPN SIQALDLSET GIQEVPAWIK NLSRLTSLSM
VGCKKLKIIP TNINMRSLSS LDLSHCTRLK TFPEISTRLE RLNLENTGIE KVPLSINYWL
YLVDLSMRGC KSLKVFSNVP DDSMEVLDLC GEEEEEDRSL HLDLNGCKNL VSLHQLPGSL
IYLDACNCEL LETVDGFFYN PQVNVHFDNC LKLNEEAREL IQTSASSLAV LPGGELPSYF
HHQCTGSFLT IPFIKDRDIP DNLRFKACVL LSSFSGTPRT FGVSWCIFYT RKADPVGHGL
CFFAKEKLVR DHLFTFEGSF SLEKDKDHGE VVEFWLVFQI VNEQRLKGSW KWESVESDSQ
KLRIMGCGVR FLDVLGDMGG SSYQVEEKTR KVKKANPFEK NKKRKRKKKV NPVPFKDNEK
GSEDLSDTDS GSGYNNSLLS IVPRLPLIVH YN
//
