ID   A0A0D3BCB2_BRAOL        Unreviewed;       507 AA.
AC   A0A0D3BCB2;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
OS   Brassica oleracea var. oleracea.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX   NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo3g074690.1, ECO:0000313|Proteomes:UP000032141};
RN   [1] {ECO:0000313|EnsemblPlants:Bo3g074690.1, ECO:0000313|Proteomes:UP000032141}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX   PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA   Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA   Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA   Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA   Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA   Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA   Chalhoub B., Sharpe A.G.;
RT   "Transcriptome and methylome profiling reveals relics of genome dominance
RT   in the mesopolyploid Brassica oleracea.";
RL   Genome Biol. 15:R77-R77(2014).
RN   [2] {ECO:0000313|EnsemblPlants:Bo3g074690.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2015) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   AlphaFoldDB; A0A0D3BCB2; -.
DR   STRING; 109376.A0A0D3BCB2; -.
DR   EnsemblPlants; Bo3g074690.1; Bo3g074690.1; Bo3g074690.
DR   Gramene; Bo3g074690.1; Bo3g074690.1; Bo3g074690.
DR   eggNOG; KOG0156; Eukaryota.
DR   HOGENOM; CLU_001570_4_0_1; -.
DR   OMA; APMEVMV; -.
DR   Proteomes; UP000032141; Chromosome C3.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24298:SF819; CYTOCHROME P450, FAMILY 705, SUBFAMILY A, POLYPEPTIDE 15-RELATED; 1.
DR   PANTHER; PTHR24298; FLAVONOID 3'-MONOOXYGENASE-RELATED; 1.
DR   Pfam; PF00067; p450; 2.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   507 AA;  57535 MW;  0F49A38B87483CD0 CRC64;
     MVATIIVDFQ YCFIFILICF SSLLCYTLFF RKPKDSCVDF PLPPSPPSLP IIGQLHLLLS
     VLIHRSLQKL SSKYGSNLYL RIFGFPIVLV SSASVAYEIF RAHDVNISSR GFLPTDDSLF
     AGSFSIISAP YGDYWKFMKK VLVTNLLGPQ ALERSRRVRG DELDRFYNNL FDKAVKKETV
     EICEEALKLT INSICKLIMG RCCLEEGGVV ERVKGLANEL DFVGKHVAPM EVMVVSNRLN
     ELLEKVLVEY EEKQGEHHLQ GMDLMDVLLA AYRDEKAEYK ITRNHIKSFY ADLLFAGITP
     SVQTIQWTLA EIINSPNTLK RMRGELDSVV GTVRLIQETD LPSLPYLQAV VKEGCRIGGF
     YVPEKTSPMI NDCAVMRDPD YWVDPDEFKP ERFLDTWQEE ERKEQALKYI PFGSGRRSCP
     GENLAFLFIG TAIGVMVQGF EWRFKEDKVN MEETVVGLSL TMAHPLKCTP VARTFNSLTL
     NLKSCDFSGT LKRQACRGPS IFSNYFT
//