ID A0A0D3CK06_BRAOL Unreviewed; 659 AA.
AC A0A0D3CK06;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=RNA exonuclease 4 {ECO:0000256|ARBA:ARBA00016937};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo5g127470.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo5g127470.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo5g127470.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the REXO4 family.
CC {ECO:0000256|ARBA:ARBA00010489}.
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DR AlphaFoldDB; A0A0D3CK06; -.
DR STRING; 109376.A0A0D3CK06; -.
DR EnsemblPlants; Bo5g127470.1; Bo5g127470.1; Bo5g127470.
DR Gramene; Bo5g127470.1; Bo5g127470.1; Bo5g127470.
DR eggNOG; KOG1198; Eukaryota.
DR eggNOG; KOG2249; Eukaryota.
DR HOGENOM; CLU_416431_0_0_1; -.
DR OMA; GGEMRVM; -.
DR Proteomes; UP000032141; Chromosome C5.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR CDD; cd05289; MDR_like_2; 1.
DR CDD; cd06144; REX4_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR037431; REX4_DEDDh_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR43482; PROTEIN AST1-RELATED; 1.
DR PANTHER; PTHR43482:SF1; PROTEIN AST1-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000032141}.
FT DOMAIN 85..269
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
FT DOMAIN 335..657
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 659 AA; 72896 MW; 65CD4DA21760D172 CRC64;
MSSDLKRKPK KKNPKPVQIN PNWSLLQQKL KSDSNNSGNR KSSNNDDSDN PRSILGKRKE
RPDTEVDVPK ISPLAPVNDD SSLTDEVAMD CEMVGVSQGT KSALGRVTLV NKWGNVLYDE
FVRPVERVVD FRTHISGIRP RDLRKAKDFR VAQTKVAELI KGKILVGHAL HNDLKVLLLT
HPKKDIRDTA EYQPFLKYFS HLTNPSFLSS SCPNEPICNL PNRDKTRKSL KHLASEFLGA
DIQNGEHCPI DDARAAMLLY QKNRREWERN VKDQTRMRLK QKKQEADFRI DGGEIRVMRS
LRGSSMAGLV SHPARLSSLR SIFTGCRAVM LPRFGGPEVL ELRENVPVPN LNPNEVLVRA
RAVSVNPLDC RIRAGYGRSV LQPHLPVIIG RDISGEVAAV GNSVKAFKVG QEVFGALHPT
ALRGTYTDYG ILSEEELTEK PSSVSHVEAS AIPFAALTAW RALKSNARIL EGQRLLVFGG
GAVGFAAIQL GVAFGCHVTA SCVGQTKDRI LAAGAEQAVD YLTEDIEVAV KGKFDAVLDT
IGRPETERIG INFLRKGGNY MTLQGEAASL TDRYGFLIGL PLATSLLAKK KIQYQYSHGI
DYWWTYMRAD PEGLAEIQRL VGAGKLKIPV EKTFPITEVV AAHEAKEKKL VPGKVVLEL
//
