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Database: UniProt
Entry: A0A0D3VEV2_9BACL
LinkDB: A0A0D3VEV2_9BACL
Original site: A0A0D3VEV2_9BACL 
ID   A0A0D3VEV2_9BACL        Unreviewed;       448 AA.
AC   A0A0D3VEV2;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   25-OCT-2017, entry version 21.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=UB51_22075 {ECO:0000313|EMBL:AJS60700.1};
OS   Paenibacillus sp. IHBB 10380.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae;
OC   Paenibacillus.
OX   NCBI_TaxID=1566358 {ECO:0000313|EMBL:AJS60700.1, ECO:0000313|Proteomes:UP000032320};
RN   [1] {ECO:0000313|EMBL:AJS60700.1, ECO:0000313|Proteomes:UP000032320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IHBB 10380 {ECO:0000313|EMBL:AJS60700.1,
RC   ECO:0000313|Proteomes:UP000032320};
RX   PubMed=25908145;
RA   Pal M., Swarnkar M.K., Thakur R., Kiran S., Chhibber S., Singh A.K.,
RA   Gulati A.;
RT   "Complete Genome Sequence of Paenibacillus sp. Strain IHBB 10380 Using
RT   PacBio Single-Molecule Real-Time Sequencing Technology.";
RL   Genome Announc. 3:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP010976; AJS60700.1; -; Genomic_DNA.
DR   RefSeq; WP_044879158.1; NZ_CP010976.1.
DR   EnsemblBacteria; AJS60700; AJS60700; UB51_22075.
DR   KEGG; pih:UB51_22075; -.
DR   PATRIC; fig|1566358.3.peg.4819; -.
DR   KO; K02313; -.
DR   Proteomes; UP000032320; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032320};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032320}.
FT   DOMAIN      142    270       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      354    423       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     150    157       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   448 AA;  51257 MW;  FFAE0C31A468B567 CRC64;
     MDSHTSELWQ EILSIIQTKL SKPSFDTWFK ATKATQINDH FIVISAPTTF AVEWLESRYT
     KMVSSTLFEV MGKQLDVKFV IEEAKPEYPA PQQVTPQPQV LQEESLTHML NPKYTFDTFV
     IGSGNRFAHA ASLAVAEAPA KAYNPLFLYG GVGLGKTHLM HAIGHYILEH NPNSKVVYLS
     SEKFTNEFIN SIRDNRTENF RNKYRSVDIL LVDDIQFIAG KESTQEEFFH TFNALHEERK
     QIIISSDRPP KEIPTLEERL RSRFEWGLIT DIQPPDLETR TAILRKKAKA ENLDIPNETM
     MYIAGQIDTN IRELEGALIR VVAYSSLTNQ DVTTHLAAEA LKDIIPSSRP RMISIQDIQQ
     RVGEYYNLRM EDFKARKRTK AVAFPRQIAM YLSRELTDFS LPKIGEAFGG RDHTTVIHAH
     DKITQALKVD QDLFKVVNNL TEKIKNPT
//
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