ID A0A0D5ACZ7_9NOCA Unreviewed; 556 AA.
AC A0A0D5ACZ7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:AJW40760.1};
GN ORFNames=NY08_2746 {ECO:0000313|EMBL:AJW40760.1};
OS Rhodococcus sp. B7740.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1564114 {ECO:0000313|EMBL:AJW40760.1, ECO:0000313|Proteomes:UP000032410};
RN [1] {ECO:0000313|EMBL:AJW40760.1, ECO:0000313|Proteomes:UP000032410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7740 {ECO:0000313|EMBL:AJW40760.1};
RX PubMed=25931596;
RA Zhang D., Li L., Zhu S., Zhang N., Yang J., Ma X., Chen J.;
RT "Complete Genome Sequence of Rhodococcus sp. B7740, a Carotenoid-Producing
RT Bacterium Isolated from the Arctic Sea.";
RL Genome Announc. 3:0-0(2015).
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC {ECO:0000256|ARBA:ARBA00005381}.
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DR EMBL; CP010797; AJW40760.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D5ACZ7; -.
DR STRING; 1564114.NY08_2746; -.
DR KEGG; rhb:NY08_2746; -.
DR PATRIC; fig|1564114.4.peg.2703; -.
DR HOGENOM; CLU_025433_2_1_11; -.
DR Proteomes; UP000032410; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 71..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 296..348
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 380..503
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 556 AA; 58684 MW; 25B0ACF2DD03EF8F CRC64;
MLVIAVVPSI VEKAVGNCYG DYQVLSDTGS RSGRSSWILF AGPLEFERAE HGEPPVIAAL
RSALERRPMR LYAVGMVSAN AIGAVIVFVL ARFVLPLPVG SEEILSDRNY LAFFVYLPVA
IAIGIGLGLR VAAPLIRWLH TGGTPTDETA IAVVRLPLRQ LGVHVLLWAL GVAVFVSVNA
SAGAALSIIV AIAVSFGGLA TCSLGYLVAE RTLRPITAAV MDVGAVTDSA ALGVRLRVVL
IWVLSTAIPV LGLGLIGLGR LIDTVIPPDV DLSPAMVSLS AVALVVGFGG MFLVGRSVSD
PLQQVSSAMQ RVEAGATDTR VDVYDASEIG RLQNGFNKMV VGLDERERLR SLFGRHVGQD
VAQRALASAP RLGGENRTVA VLFVDLVGST ARAERESAEA VVDWLNRFFA VVVEHGERGG
GFVNKFEGDA ALLIFGAPVD HPDPATAALR TARTLAAELS IDGDYELGIG VTYGSVIAGN
IGAESRFEYT VIGDTVNQAA RLTDLAKDDP DTDVLTSSTV LDHASDDERT HWTTGETVTL
RGRSTPTILA APVRPR
//
