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Entry: A0A0D5VCZ7_9BURK
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ID   A0A0D5VCZ7_9BURK        Unreviewed;       544 AA.
AC   A0A0D5VCZ7;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-SEP-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AJZ59986.1};
GN   ORFNames=OI25_1458 {ECO:0000313|EMBL:AJZ59986.1};
OS   Paraburkholderia fungorum.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=134537 {ECO:0000313|EMBL:AJZ59986.1, ECO:0000313|Proteomes:UP000032614};
RN   [1] {ECO:0000313|EMBL:AJZ59986.1, ECO:0000313|Proteomes:UP000032614}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-463 {ECO:0000313|EMBL:AJZ59986.1,
RC   ECO:0000313|Proteomes:UP000032614};
RX   PubMed=25931592;
RA   Johnson S.L., Bishop-Lilly K.A., Ladner J.T., Daligault H.,
RA   Jaissle J., Frey K.G., Koroleva G.I., Bruce D.C., Coyne S.R.,
RA   Broomall S.M., Li P., Teshima H., Gibbons H.S., Palacios G.F.,
RA   Rosenzweig C.N., McMurry K., Redden C.L., Xu Y., Currie B., Mayo M.,
RA   Minogue T.D., Chain P.S.;
RT   "Complete genome sequences for 59 burkholderia isolates, both
RT   pathogenic and near neighbor.";
RL   Genome Announc. 3:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP010026; AJZ59986.1; -; Genomic_DNA.
DR   RefSeq; WP_046567229.1; NZ_CP010026.1.
DR   EnsemblBacteria; AJZ59986; AJZ59986; OI25_1458.
DR   KEGG; bfn:OI25_1458; -.
DR   PATRIC; fig|134537.4.peg.1576; -.
DR   KO; K02313; -.
DR   Proteomes; UP000032614; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032614};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032614}.
FT   DOMAIN      241    375       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      452    521       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     249    256       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      135    162       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   544 AA;  59509 MW;  F79B9769C1894824 CRC64;
     MNDFWQHCSA LLERELTPQQ YVTWIKPLAP VAFDADANTL SIAAPNRFKL DWVKSQFSGR
     IADLARDFWH TPVDVQFVLD PKAGMRAPAA ASSAPARPAS ASGSMGAGHS SGSNGGGAAV
     DAAVGAVQAS QAARANSANS AMANLNANAR AAADQNANAR AAAEDAADLD LPSLDANEAA
     AARRTWRPGQ SASSNGNGEN DSMYERSKLN PVLTFDNFVT GKANQLARAA AIQVADNPGI
     SYNPLFLYGG VGLGKTHLIH AIGNQLLMDK AGARIRYIHA EQYVSDVVKA YQRKAFDDFK
     RYYHSLDLLL IDDIQFFSGK SRTQEEFFYA FEALVANKAQ VIITSDTYPK EISGIDDRLI
     SRFDSGLTVA IEPPELEMRV AILMRKAQSE FVSLNEDVAF FVAKHLRSNV RELEGALRKI
     LAYSKFHGRE ITIEVTKEAL KDLLTVQNRQ ISVENIQKTT ADFYSIKVAD MYSKKRPANI
     ARPRQIAMYL AKELTQKSLP EIGELFGGRD HTTVLHAVRK IAAERGTDAQ LNHELHVLEQ
     TLKG
//
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