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Database: UniProt
Entry: A0A0D5YPD6_9FLAO
LinkDB: A0A0D5YPD6_9FLAO
Original site: A0A0D5YPD6_9FLAO 
ID   A0A0D5YPD6_9FLAO        Unreviewed;       474 AA.
AC   A0A0D5YPD6;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   25-OCT-2017, entry version 21.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=VC82_2 {ECO:0000313|EMBL:AKA33696.1};
OS   Muricauda lutaonensis.
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Muricauda.
OX   NCBI_TaxID=516051 {ECO:0000313|EMBL:AKA33696.1, ECO:0000313|Proteomes:UP000032726};
RN   [1] {ECO:0000313|EMBL:AKA33696.1, ECO:0000313|Proteomes:UP000032726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC-HSB-11 {ECO:0000313|EMBL:AKA33696.1,
RC   ECO:0000313|Proteomes:UP000032726};
RA   Kim K.M.;
RT   "Complete genome sequence of Muricauda lutaonensis CC-HSB-11T,
RT   isolated from a coastal hot spring.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP011071; AKA33696.1; -; Genomic_DNA.
DR   RefSeq; WP_045800571.1; NZ_CP011071.1.
DR   EnsemblBacteria; AKA33696; AKA33696; VC82_2.
DR   KEGG; mlt:VC82_2; -.
DR   PATRIC; fig|516051.4.peg.2; -.
DR   KO; K02313; -.
DR   Proteomes; UP000032726; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032726};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032726}.
FT   DOMAIN      172    302       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   474 AA;  54215 MW;  FF53AF61F8D30DCC CRC64;
     MNVTADSVWN NCLVFIKDNI QPQAFKTWFE PIKPVRLTDN ALSIQVPSKF FYEWLEEHYV
     KLLKVALTKE LGQNAKLVYV IKMENKYGNS EPFTEKIPSS NRSSMDPQEL NVPITSKNPQ
     LKNPFVIPGI RNIKIESQLN PNYNFENFLE GDSNRLARSA GLAVANKPGG TSFNPLLIFG
     GVGLGKTHLA HAIGVEIKDK YPEKTVLYIS AEKFTQQYIE SVKKNTRNDF IHFYQLIDTL
     IIDDVQFLSG KSGTQDVFFH IFNHLHQNGK QVILTSDKAP VDMQDIEQRL LSRFKWGLSA
     ELQSPDYETR VSILKNKLYR DGVEMPEEII DHVAKNIKTN IRELEGAIIS LIAQSSFNKK
     EVTLELAQQV VEKFVKNTKR EVSIDYIQKV VSDYFEMDVA TLQSKTRKRH IVQARQLAMF
     FAKKYTKASL ASIGSQIGKR DHATVLHACK TVDNLAETDK QFRKYLEDLN KKFT
//
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