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Database: UniProt
Entry: A0A0D6A1I7_9LACO
LinkDB: A0A0D6A1I7_9LACO
Original site: A0A0D6A1I7_9LACO 
ID   A0A0D6A1I7_9LACO        Unreviewed;       456 AA.
AC   A0A0D6A1I7;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   25-OCT-2017, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=LBAT_0001 {ECO:0000313|EMBL:BAQ56390.1};
OS   Lactobacillus acetotolerans.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=1600 {ECO:0000313|EMBL:BAQ56390.1, ECO:0000313|Proteomes:UP000035709};
RN   [1] {ECO:0000313|EMBL:BAQ56390.1, ECO:0000313|Proteomes:UP000035709}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 13120 {ECO:0000313|EMBL:BAQ56390.1,
RC   ECO:0000313|Proteomes:UP000035709};
RA   Toh H., Morita H., Fujita N.;
RT   "Complete genome sequence of Lactobacillus acetotolerans NBRC 13120.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; AP014808; BAQ56390.1; -; Genomic_DNA.
DR   RefSeq; WP_060458989.1; NZ_AP014808.1.
DR   EnsemblBacteria; BAQ56390; BAQ56390; LBAT_0001.
DR   KEGG; lae:LBAT_0001; -.
DR   PATRIC; fig|1600.4.peg.1; -.
DR   KO; K02313; -.
DR   Proteomes; UP000035709; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000035709};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035709}.
FT   DOMAIN      152    281       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      364    433       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     160    167       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   456 AA;  52314 MW;  7BAD191DBF0C768C CRC64;
     MFDIDKFWQH FNDEMRERFN EVAYNAWFKN TKPISYNKGT HELKIAVQNP VAKGYWEKNL
     SSQLIQSAYG YVNIEILPTF HVADDSKSPE RMVTPKPKTA RPLHTSKAPD HEDFMRDLQL
     NDKYTFDNFV QGEGNKLAAG AALAVADSPG SFYNPLFIFG GVGLGKTHLM QAIGHQMLAE
     RPNSKVVYIQ SETFVNDFIN SIKNKTQDQF REKYRTCDLL LVDDIQFFAK KEGIQEEFFH
     TFETLYNDQK QIVMTSDRLP TEIPDLSERL VSRFAWGLQV EITPPDLETR IAILRKKAEA
     EHLTIDDNTL DYIASQVDTN IRELEGALVK VQAHATIEKE DINVNLAREA LADLKLVQKD
     RGLQISKIQE VVANYFQTST TELKGKRRVR QIVVPRQIAM YLSRELTDAS LPKIGQEFGG
     KDHTTVMHAY QKISRQIKTD SDIKTAVFDL KQMLDR
//
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