ID A0A0D6KRP5_9CYAN Unreviewed; 612 AA.
AC A0A0D6KRP5;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cell division protein {ECO:0000313|EMBL:EKF02174.1};
GN ORFNames=FDUTEX481_06897 {ECO:0000313|EMBL:EKF02174.1};
OS Tolypothrix sp. PCC 7601.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Tolypothrichaceae;
OC Tolypothrix.
OX NCBI_TaxID=1188 {ECO:0000313|EMBL:EKF02174.1, ECO:0000313|Proteomes:UP000032761};
RN [1] {ECO:0000313|EMBL:EKF02174.1, ECO:0000313|Proteomes:UP000032761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7601 / UTEX B 481 {ECO:0000313|Proteomes:UP000032761};
RX PubMed=25953173;
RA Yerrapragada S., Shukla A., Hallsworth-Pepin K., Choi K., Wollam A.,
RA Clifton S., Qin X., Muzny D., Raghuraman S., Ashki H., Uzman A.,
RA Highlander S.K., Fryszczyn B.G., Fox G.E., Tirumalai M.R., Liu Y., Kim S.,
RA Kehoe D.M., Weinstock G.M.;
RT "Extreme Sensory Complexity Encoded in the 10-Megabase Draft Genome
RT Sequence of the Chromatically Acclimating Cyanobacterium Tolypothrix sp.
RT PCC 7601.";
RL Genome Announc. 3:0-0(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF02174.1}.
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DR EMBL; AGCR01000033; EKF02174.1; -; Genomic_DNA.
DR RefSeq; WP_045870319.1; NZ_JH930360.1.
DR AlphaFoldDB; A0A0D6KRP5; -.
DR STRING; 1188.FDUTEX481_06897; -.
DR PATRIC; fig|1188.3.peg.3984; -.
DR HOGENOM; CLU_009289_1_2_3; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000032761; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000313|EMBL:EKF02174.1};
KW Cell division {ECO:0000313|EMBL:EKF02174.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..238
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 271..584
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 523..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 66844 MW; 285F289C40D0B03F CRC64;
MDFIPSALPG SKKDTRTVGR GFQSVFLIIF TLIMTAGIDA RLAYLQIVEG PKLRQRAESN
RIRMIPKQPE RGNIFDRNGK LLASTRYPHS VYLWPMAHTK PSWPIVAPRL EKILNTSQDE
MEKKLKLAGA NSSSLVRIAR DISEAEITAL KEYANELPGV EINTEAVRYY PEGLALAHVL
GYTRELTPEQ LEKRKQEGYR LGDVIGQMGV EKAYEKILRG EWGGQQVEVD GAGRPIRVLG
EKQAKAGNDL HLTIDINLQK AADQALGKYQ GAVVAIDPNN GAVLAMASHP TFDPNIFSKQ
KLSQKDWESV QGKDHPLVNR ALSAFPPAST FKIITASAGL ETGKFSPDTV LQTFGSLTVG
GVTFGEWNHA GFGPLGFPRA LAMSSDTFFY QVGRRVGGPD LIAWSRKYGF GQKTGIEFPD
EESKGLVPDE KWKQKAWKMP WTVGDTINMS IGQGALQVTP LQSAIMFSVP ANGGYRVKPH
LLKDHEEAKS WRVSLNMKPS TIKVLRDGLR KVVSEGTGKR LDVPTIAPAS GKSGTAEAGV
GRPNHTWFGA YAPSDKPEIV VVGFGENSGD HGGTVCGPMA LQVLEAYFQH KYPGKYQKPV
SEGNHNGGST GD
//
