ID A0A0D6KZR3_9CYAN Unreviewed; 1406 AA.
AC A0A0D6KZR3;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=FDUTEX481_01135 {ECO:0000313|EMBL:EKF04971.1};
OS Tolypothrix sp. PCC 7601.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Tolypothrichaceae;
OC Tolypothrix.
OX NCBI_TaxID=1188 {ECO:0000313|EMBL:EKF04971.1, ECO:0000313|Proteomes:UP000032761};
RN [1] {ECO:0000313|EMBL:EKF04971.1, ECO:0000313|Proteomes:UP000032761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7601 / UTEX B 481 {ECO:0000313|Proteomes:UP000032761};
RX PubMed=25953173;
RA Yerrapragada S., Shukla A., Hallsworth-Pepin K., Choi K., Wollam A.,
RA Clifton S., Qin X., Muzny D., Raghuraman S., Ashki H., Uzman A.,
RA Highlander S.K., Fryszczyn B.G., Fox G.E., Tirumalai M.R., Liu Y., Kim S.,
RA Kehoe D.M., Weinstock G.M.;
RT "Extreme Sensory Complexity Encoded in the 10-Megabase Draft Genome
RT Sequence of the Chromatically Acclimating Cyanobacterium Tolypothrix sp.
RT PCC 7601.";
RL Genome Announc. 3:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF04971.1}.
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DR EMBL; AGCR01000005; EKF04971.1; -; Genomic_DNA.
DR RefSeq; WP_045868099.1; NZ_JH930357.1.
DR STRING; 1188.FDUTEX481_01135; -.
DR PATRIC; fig|1188.3.peg.1139; -.
DR HOGENOM; CLU_252075_0_0_3; -.
DR OrthoDB; 518094at2; -.
DR Proteomes; UP000032761; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 6.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 8.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 6.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 7.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00116; CBS; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 8.
DR SMART; SM00091; PAS; 6.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 8.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 8.
DR PROSITE; PS50112; PAS; 5.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Kinase {ECO:0000313|EMBL:EKF04971.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:EKF04971.1}.
FT DOMAIN 10..67
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 74..134
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 173..219
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 222..274
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 275..347
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 351..404
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 485..536
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 610..665
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 666..740
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 738..794
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 874..926
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 927..1004
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1006..1058
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1059..1114
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1132..1184
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1188..1405
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 1406 AA; 160023 MW; 21CBD6215130235F CRC64;
MQPLSQTQFL QKCPLTLAPN TSVEFAVQAM NQENSSYVLV VEQHQLVGIF TQRDLVKAIA
SGVNLSVATL SDVMTDNVIT VKESELGDLF KILRLLKQQQ ISYLPVLDKE GKLVGAIALA
NMQAALLLEI EHREQVAQTQ PNYQTQLDVI LSSTRTIISR IRLLSAPEFR CEYISPSCQS
ILGYSPDEFL ADPLLWASRL LPEDQNVILH HIQDAIQSEK ILTIEYPFSH KDGSICWICD
TFSSEWDEIT QSWQVMSVKT DITQRKQTEE ALRTSEERLQ LALEASGEGV WDWNIITGYL
YLSPRWCEML GYAADELADD ITTWEQLLHP EDRPWVMDVL QSHLMDSSIP YTFEYRMRTK
SEGWKWIANY GKVVSRDKNG QALRMAGIHR NVTNRKRAEQ ALQEREAFLR AIGDNIPHSY
IYQVIRERDG NYRFYYISAG VEATNGFHPT AVLADSSLLY NNLLPEDQLY VSQKQEESAQ
TMSVFDVQVR EYTPQRDIRW IRLCSTPRHL DDGRICWDGI RLDITEQKLT EERLRKSTAL
LTEAQQVAQI GNWEYDLATQ KITWTEELFH ILNRDPALLE PSYDENLQIY QPQDAARLHK
AVETTITTGE SYKLILKRNP RPDGSIRYIE GTGQAEFNAD GQVIRLYGTA QDITERFLAQ
QSLQKKEEFL SSIYNGVEQC IFVVDVLVDG EISFVDINPA YERLTGISAL DIQGKTLDKL
LPPEVASLVR QHYQACVTAR ETVTYEECLP ISGQDTWWIT SLTPLLDENS CVYRIVGSST
NISDRKRLEL ALQASESRLN NILTTANASI VCFRVFANYD WEYEYQSIGS EALFGYTPAE
IVSDKQMWMS QVFAEDREQV LYPLFEEILA ERTSTIEYRF HHKDGSLRWI SATYSSHRDK
VANCWIVTGV SIDISDRKRL ELALQASEKR LQNILSTASA SIFSFRISAN QEWEYEYQSA
ASEIIFGYSP AEILADKKLW ISRVLPEDRK QVMYARFQRS IAEGTNSIEY RFRHKDGAVR
WISTTYSSVR QEETDTWVVI GVSIDVSSLK LAEEAMRQSE TLFRTLSDSA PVGIFRSDTL
GTNIYTNPRF QAICGLSLEE SFGDSWLQYI HPEDLAVFWP QWQELATVNL EFCTELRYIR
PDSTLRFLRI TIVPIISSPH EIIGYVGTIE DITESRAIEK MKNEFISIVS HELRTPLASI
RGALGLLSSG VLKTQPETAQ QMLDIAYSDT ERLVRLVNDI LDLEHLESNK FSLVKQRCDA
ATLIRQSVEA LQPLATANNV VLEMSLTSIQ ICVDPDRIMQ TLLNLIGNAI KFSPANSTVT
LSAEDLSDRI LFKVQDQGRG IPHDMLETIF GRFQQVDASD SRQKGGTGLG LAICRGIVQQ
HGGTIWAQSV LGEGSIFYFT IPKPEV
//
