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Database: UniProt
Entry: A0A0D7W9Z8_9FLAO
LinkDB: A0A0D7W9Z8_9FLAO
Original site: A0A0D7W9Z8_9FLAO 
ID   A0A0D7W9Z8_9FLAO        Unreviewed;       475 AA.
AC   A0A0D7W9Z8;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-SEP-2017, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=PK35_02015 {ECO:0000313|EMBL:KJD34582.1};
OS   Tamlana nanhaiensis.
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Tamlana.
OX   NCBI_TaxID=1382798 {ECO:0000313|EMBL:KJD34582.1, ECO:0000313|Proteomes:UP000032361};
RN   [1] {ECO:0000313|Proteomes:UP000032361}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FHC16 {ECO:0000313|Proteomes:UP000032361};
RX   PubMed=25735434; DOI=10.1007/s10482-015-0410-x;
RA   Liu X., Lai Q., Du Y., Li G., Sun F., Shao Z.;
RT   "Tamlana nanhaiensis sp. nov., isolated from surface seawater
RT   collected from the South China Sea.";
RL   Antonie Van Leeuwenhoek 107:1189-1196(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KJD34582.1}.
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DR   EMBL; JTDV01000001; KJD34582.1; -; Genomic_DNA.
DR   RefSeq; WP_044624967.1; NZ_JTDV01000001.1.
DR   EnsemblBacteria; KJD34582; KJD34582; PK35_02015.
DR   PATRIC; fig|1382798.3.peg.407; -.
DR   Proteomes; UP000032361; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032361};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032361}.
FT   DOMAIN      172    308       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   475 AA;  54234 MW;  B12C70000E456062 CRC64;
     MSKTAKSVWN NCLLFIKDNI QPQAYKTWFE PIVAVKLTDN ALSIQVPSKF FYEWLEEHYV
     KILKVALTKE LGETAKLVYI IKMENTYGNK QPFTEKIPSS HRTAVKSQDV DIPLNNKSRE
     LKNPFIIPGI RNVKIESQLN PNYSFENFLE GDSNRLARSA GLAVASKPGG TSFNPLLIFG
     HVGLGKTHLA HAIGVDIKDK YPEKTVLYIS AEKFTQQYIE AVKKNNRNDF IHFYQIIDVL
     IIDDVQFLSG KSGTQDVFFH IFNHLHQNGK QVVLTSDKAP VDMQDIEQRL LSRFKWGLSA
     ELHNPDFETR VSILKNKLYR DGVVMPDDIV DYIAKNIKSN VRELEGAIIS LIAQASFNKK
     EVTIDLARVI VEKFVKNTKR EVSIDYIQKV VSDYFQMDIE TLQSKTRKRH IVQARQLAMF
     FAKKFTKASL ASIGSQIGKR DHATVLHACK TVDNLSSTDK QFRKYVEDIT KKLSV
//
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