ID A0A0D8XGL7_DICVI Unreviewed; 1171 AA.
AC A0A0D8XGL7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DICVIV_11126 {ECO:0000313|EMBL:KJH42889.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH42889.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH42889.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH42889.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
CC -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
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DR EMBL; KN716614; KJH42889.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XGL7; -.
DR STRING; 29172.A0A0D8XGL7; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR Gene3D; 3.10.20.360; CKK domain; 1.
DR InterPro; IPR032940; CAMSAP.
DR InterPro; IPR022613; CAMSAP-like_CH_dom.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR038209; CKK_dom_sf.
DR InterPro; IPR014797; CKK_domain.
DR InterPro; IPR011033; PRC_barrel-like_sf.
DR PANTHER; PTHR21595:SF0; PATRONIN; 1.
DR PANTHER; PTHR21595; UNCHARACTERIZED; 1.
DR Pfam; PF11971; CAMSAP_CH; 1.
DR Pfam; PF08683; CAMSAP_CKK; 1.
DR SMART; SM01051; CAMSAP_CKK; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50346; PRC-barrel domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51508; CKK; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|PROSITE-
KW ProRule:PRU00841}; Reference proteome {ECO:0000313|Proteomes:UP000053766}.
FT DOMAIN 169..304
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1031..1168
FT /note="CKK"
FT /evidence="ECO:0000259|PROSITE:PS51508"
FT REGION 411..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 965..1019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 901..953
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 782..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..824
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..870
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 972..1003
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1171 AA; 131250 MW; 5D4FE4F34F9226F0 CRC64;
MDEPILPPLI PLEHYVETEG KLAASIRWLI LRVYGQEKYI PDKLRISGLR DESGHLQLDI
AIVTGLTNGS LYCQAAAKIF KDPQLVTKSH GAVLAALTDC GVDVVQCNNG TTANVTEDEL
FTADSFQMAA HLAMIDALML AHLRNVITVD RVIDAVSRHT TVDESERPMD SVDALLFWIN
KICLLVRDDV ERSQIRLRVG LLGGAEGGII PEMEDLYNDI SDGQCLCALV AWYRPREMDI
EDVCYNDLMS NADCHYNLLI LKQFCHNCLP WNPFHFEIED ILYLRESLQM NINVFLSDLF
DIFEPSPAMV VQAEPVTSPR RFVPVQCIPD LRAANSAARC PHPPRVRNPF NNVLVTSSQG
VASALPSRSM SMMSQDSLVT NRTSDSFRNN TQRQAQELWG TNVTNFVSLV QPDESSNGST
STTVSPYARS DSLPTASIRL ALKEKRRDHE KRKALISTMT ESERVEKGKA AFFAVMSRCD
PSSAAGSESP DSKLIRELDR KLTDLAQRVS LMNTSDQQRM SRALSQPSVY QEVPQISASS
ARTGYATLPH NISSSATPSY AQPQEFYEYA QPQQLRSSFS NGMLNYLPGQ MPSFGEYPTG
LVQPQHVQTQ PVYPPDMYTS SISGAFTPRP RQSDYAMMHQ STHIANGFTL HQPAASRIVA
PQVSSYSSSL YAQTPLDTHT SFSYTMQPQM ITTVTPQQSC AQAFSYQGTS QCENQSPFVY
DSQDGGMTFR LHSQDATSSR IDPPLEISRN LTNWGITYQQ GHTGRLQRRT WENQTFIKSQ
QDLVNQPDLV PTVPSDDDQN HQQTFAVENL RRSRESRDRN DIGSPESHIS TMEYGLPHDR
DVPSQPSPPR DPANHMNGSA SESTRNAVSS GPAFVVSDEH VADDFDEIAE QRRQARRAAL
LAKTMKRKEE IENKIDQIEQ RNAEKRMAEI AKREMAEQRK LEKELQRQVL RQKILDDYKR
RKMEKELGVE SGSNSARGSS GRGHSQPPFI RTKSQMSESV VDGSDKTRQP RMRGQSTVEQ
RFAVQSLQEP THKLFAKAAP KSNRGLIINA LQYSVFPGAV NDGTRIKTMN DLAASDAKHF
LVLFRDYKCQ YRGLYSWDQV SDTAIKISGQ GPSKCSESIM KLMFKYDSGA KNFSQIPTKH
LSATIDGFTI QDQFWQKPKI PYSGAVSHRN N
//
