ID A0A0D8XL56_DICVI Unreviewed; 555 AA.
AC A0A0D8XL56;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Serine/threonine protein phosphatase 2A regulatory subunit {ECO:0000256|PIRNR:PIRNR028043};
GN ORFNames=DICVIV_08604 {ECO:0000313|EMBL:KJH45358.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH45358.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH45358.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH45358.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SIMILARITY: Belongs to the phosphatase 2A regulatory subunit B56
CC family. {ECO:0000256|ARBA:ARBA00009745}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN716412; KJH45358.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XL56; -.
DR STRING; 29172.A0A0D8XL56; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0000159; C:protein phosphatase type 2A complex; IEA:UniProtKB-UniRule.
DR GO; GO:0019888; F:protein phosphatase regulator activity; IEA:UniProtKB-UniRule.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002554; PP2A_B56.
DR PANTHER; PTHR10257; SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B; 1.
DR PANTHER; PTHR10257:SF3; WELL-ROUNDED, ISOFORM B; 1.
DR Pfam; PF01603; B56; 1.
DR PIRSF; PIRSF028043; PP2A_B56; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053766}.
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 64754 MW; A3CDBD9AB56B5545 CRC64;
MLKSKKKDKE GKEKHSGPVI PRRDRRQSSS LFNVSSNREL VKLPPIKEAD LAEREDLFIQ
KLRQCCVVFE FVQDPLSDMK YKEVKRAALN ELIDYVSTCR DAITDNIYPE AINMFAVNLF
RPLSPPTNPV GAEFDPDEDE PTLEAAWPHL QLVYEFFLRF LESPDFQSSI AKKYIDHKFI
SRLLMIMDSE DPRERDFLKT TLHRIYGKFL GMRAYIRKQV NNIFYCFIYE TERHNGIAEL
LEILGSIING FALPLKEEHR TFLLRVLLPL HKVKSLSTYH PQLAYCVVQF LEKDPSLTEP
VIMGLLKFWP KIHSPKEVMF LNELEEVLDV IEPVEFQKVM VPMFTQLARC VSSPHFQVAE
RALYYWNNEY VMSLIGENAS VILPIMFPAL YKNSKSHWNK TIHGLVYNAL KLLMEINQKL
FDECSQNYAK ERTLEKIRQE EKEKKWELIE QSARKNPKYG EIQSIFGNVN GITSGMDALS
LKSTLTTASD DETVHLSKEE IIRNMLNREN VEQTNQRELG FTQKLSELPP DRQTEKALEE
YKRHDAYLRK LGNAE
//
