ID A0A0D8XUG3_DICVI Unreviewed; 509 AA.
AC A0A0D8XUG3;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Unspecific monooxygenase {ECO:0000313|EMBL:KJH47394.1};
GN ORFNames=DICVIV_06515 {ECO:0000313|EMBL:KJH47394.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH47394.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH47394.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH47394.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KN716309; KJH47394.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XUG3; -.
DR STRING; 29172.A0A0D8XUG3; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24291:SF189; CYTOCHROME P450 4V2; 1.
DR PANTHER; PTHR24291; CYTOCHROME P450 FAMILY 4; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766}.
SQ SEQUENCE 509 AA; 58843 MW; FE4DC48E7EAC7BBA CRC64;
MGLFAVALVI AALTWISNFL YKRIKYVLKQ IAVFQGPVAL PLIGNLTQFH FKPEEFFEQA
QGLAYMLRNG EDRICRIWFG PIPFVLLYGP KECEAVLGSN KLLNKPIQYS FLSPWIGEGL
LISKPDKWRS RRKLLTPTFH YEILKDFVEV YNRHGQTLLE KFLKNADRGQ YEDIFHTVTL
CTLDVICEAA LGICIDAQKK PHSPYLEAVF RMKVIVQQRQ VKPQYYSQLI FDLFGDGKEQ
QQCVKILHEF TGNTLSLQIM VVQRQVFVLH TVNGLGRRRM AFLDLMLDMH SKGELSMEGI
QEEVDTFTFE GHDTTSASIN WFLHLMGAHP HIQEKVQREV DEVLGETDRT PTYEDLGSLK
YLEACVKETL RLYPSVPLIA RQVVEDVKIR DHLLPAGTGV AVIPSMVHRD PNYWDDPEVF
RPERFINGEI KHPYAYIPFS AGSRNCIGQR FALMEEKCIL ALLMRHLRVR SLLRTDQMRV
AQELIIRPLY GNRLKFERRS YGDYSHCTA
//
