ID A0A0D8XXH2_DICVI Unreviewed; 635 AA.
AC A0A0D8XXH2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=TAP protein {ECO:0000313|EMBL:KJH48527.1};
GN ORFNames=DICVIV_05377 {ECO:0000313|EMBL:KJH48527.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH48527.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH48527.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH48527.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SIMILARITY: Belongs to the NXF family. {ECO:0000256|ARBA:ARBA00009285}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN716265; KJH48527.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XXH2; -.
DR STRING; 29172.A0A0D8XXH2; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR CDD; cd14342; UBA_TAP-C; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR030217; NXF_fam.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR005637; TAP_C_dom.
DR InterPro; IPR015245; Tap_RNA-bd.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR10662; NUCLEAR RNA EXPORT FACTOR; 1.
DR PANTHER; PTHR10662:SF22; NUCLEAR RNA EXPORT FACTOR 1; 1.
DR Pfam; PF09162; Tap-RNA_bind; 1.
DR Pfam; PF03943; TAP_C; 1.
DR SMART; SM00804; TAP_C; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50177; NTF2_DOMAIN; 1.
DR PROSITE; PS51281; TAP_C; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 356..523
FT /note="NTF2"
FT /evidence="ECO:0000259|PROSITE:PS50177"
FT DOMAIN 575..628
FT /note="TAP-C"
FT /evidence="ECO:0000259|PROSITE:PS51281"
SQ SEQUENCE 635 AA; 71723 MW; 623C25BEED9459DB CRC64;
MPLGRYNRRD AKNLSKNRFS RLDADIASSY VDDEEEERPR PKQGTVTRVI NMLAGRPLHG
QVGTRRGKKD EQTLRSAAGV SRNTEMVYKI RIPSGRKLTV PWIMKQLHQQ IEDIKPLLVS
ITPRGDVEFF LKSEDSADAC RAISRRIVHR VLGDRMSIIV DKVVAPWTRL NKEETAVIQT
VVDSRYNHEL RSLDLSEFAL DQQFKDRDLH MMLNKNNVML TVVDRIDEKF GYITALSLQG
NRLRFLDYAA VLTSVTKFLK VLDLSNNQID KVSELEKLKG LPVETLFFEG NPLVEQLTTA
SGYLSAVHQV FPNVCVLDGA PVQPATVHVQ SLDDDEVTCE PPCRAGFYGS DSLRVLVERF
LVEYFKLYDG EDGAITRKSL MQAYDQDNST FTLTIANLKD MPHEGPIRYP NDACYNTYIR
ASHNVLYEDR WSRNRSSLTY RGAMDIAVAL SRLPVTNHYT ESFIVDTHLI SEELMAFCVQ
GLFEDGKFAK PDDVPQLNFF ARSFLVSPRG NESIAVLSDM LYISGITSAR MARYKIMLNK
AVSAGQLPST SIPMNSVLNA AESIGVQMSS QLTVERKMQM VEQFCKDSGM LAAWSEKCLM
DYDWNYIAAG QAFLSNKNNI PKEAFASLSP DKHVS
//
