ID A0A0D8Y1G0_DICVI Unreviewed; 585 AA.
AC A0A0D8Y1G0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Leucine Rich repeat-containing domain protein {ECO:0000313|EMBL:KJH49997.1};
GN ORFNames=DICVIV_03870 {ECO:0000313|EMBL:KJH49997.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH49997.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH49997.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH49997.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN716218; KJH49997.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8Y1G0; -.
DR STRING; 29172.A0A0D8Y1G0; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF22; LEUCINE RICH REPEAT FAMILY PROTEIN; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00369; LRR_TYP; 10.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 5.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..585
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002336393"
FT TRANSMEM 505..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 437..490
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 585 AA; 65563 MW; 67E2F6D2046A93D8 CRC64;
MRLLQLLLLL LLIYEVHGII ECPRECECDA IPPNNSSWAV YCHNGGLNDT LFADILNRLP
PSLKLLDIQV NSWRPPNKFK WSDNLNRFSM LKHLRLVNCA IPAMSRSTRL PSLEILDLNG
NDIEHATMGN FGGMPNLRFL DLSNNHLSIL PTGVFTFLHN LKSLSLANNS ITELSANLLR
GLQMLKSLRL DNNHIPIKQI NDLFVDVPQL EELNLNDCQI SSIANLSLND VAQLRHLGLA
NNNLRTIPTQ ELQQLTHLAV LDLSGNDISE VGACAFCSNN ISKLDLSHNR LGLVKQPFHV
DAFRNIPLKE LDLSFNHMNE FHSSSLGWAQ EGLRTLNMAG NSLGGFHSDI TATLSSLLSL
NMAFNNIEHI PLAFPPQYYH LTALNISGNT LTYIPENLPY LLPSLKEFDI SRNKFTTLTQ
PAIDYINELE RVYLDNNPWD CSCSIQHIQQ HMRQRYGMRH ILRYHDVRCA EPELVKGQPI
LSVADINECA VLFGARYGLS QSSELFILLA ALLSAALVLS LLLICLYLLR ERQHKGSYVT
REHSRTPLTM ATHVNCSVSN SGTSEALTPP MPPPPPKATI AYFGI
//
