ID A0A0D8Y4S7_DICVI Unreviewed; 841 AA.
AC A0A0D8Y4S7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=7 transmembrane receptor {ECO:0000313|EMBL:KJH51868.1};
GN ORFNames=DICVIV_01947 {ECO:0000313|EMBL:KJH51868.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH51868.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH51868.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH51868.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN716175; KJH51868.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8Y4S7; -.
DR STRING; 29172.A0A0D8Y4S7; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd15934; 7tmC_mGluRs_group2_3; 1.
DR Gene3D; 3.40.50.2300; -; 4.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF171; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 2.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:KJH51868.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 540..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 649..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 697..716
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 728..750
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..780
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 540..802
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 841 AA; 94430 MW; 0A7D8322F87831B1 CRC64;
MLTTIFKLII PGEIVLGGLF PIHEAGRNGS SCGKIKADQG VQRMVAMLYA LEKVNQDSSI
LPQATLGAQI LDTCSVDSYA LEQTLEFIKS VMSKGDGAVC ADGSSASYHR QPVSAVVGAA
GSQVSVMVAS MLQLFKIPQV SYSSTGAELS EKSRFGYFSR VVPPDNLQAQ VMARIVRELD
WTYVHAIADT GSYGTLSFMI NNCANHSVEK KTWRIIYCGI GERGMDSFRA AATEFGICID
GDVHKISRRW TETNFRDLLI RMHHTRKARG VVMFVDEDNL KRLLHTLDKL IKEGRKELER
HFWWVSYITF FRKLSPNGFT FLEEYWDALG CGSNENLRNF GECFDYINYT LKQESYVPFV
VDTVYVLARA ISKYITDECG PIEYQRCPLS SSRFKGDRLQ NYYRNVSLIE NEPPLIDANG
DGIGRYDVFQ LDNMGIYHKV GKWRSTRDLF EIEVERVRRG FQLAPGDSPL SVCSVDCPRG
HYRAYQDQTC CWACIPCDTT TSIIINVTRC DMCPEGEVPD VNQSFCSPIP PVSMTWNSTW
ALIPACFSLL GLASTIFVVV VFLKFSNTPV IMASGRELCY CMISGISMCY LLTFFLVSQP
SVPTCAITRV LMGLSMSAIY AAIITKTNRL GRVFKPDGAQ RPRFITPKAQ VGICASIVSV
QLVGSVVWLL VDPPGTKIVF PSRTEAVLTC KATASHLLVS LLYNLILIVI CTVYAFKTRK
IPENFNETRH IGFTMYSTCI LWLSFGPIYF ATQNNFRIQI TSLCMCISLS GTVALVCFFA
PKVYIVIFQP DKNVRTRQSA VGRLVNQQMR FMRYITVEVY GSDSMIITKY EYAVVYVFSF
F
//
