ID A0A0D9QEF4_PLAFR Unreviewed; 613 AA.
AC A0A0D9QEF4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Pescadillo homolog {ECO:0000256|HAMAP-Rule:MF_03028};
GN ORFNames=AK88_04918 {ECO:0000313|EMBL:KJP85445.1};
OS Plasmodium fragile.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5857 {ECO:0000313|EMBL:KJP85445.1, ECO:0000313|Proteomes:UP000054561};
RN [1] {ECO:0000313|EMBL:KJP85445.1, ECO:0000313|Proteomes:UP000054561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=nilgiri {ECO:0000313|Proteomes:UP000054561};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Duraisingh M., Young S.K., Zeng Q., Gargeya S., Abouelleil A.,
RA Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium fragile nilgiri.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC the large ribosomal subunit. {ECO:0000256|HAMAP-Rule:MF_03028}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03028}.
CC -!- SIMILARITY: Belongs to the pescadillo family. {ECO:0000256|HAMAP-
CC Rule:MF_03028}.
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DR EMBL; KQ001725; KJP85445.1; -; Genomic_DNA.
DR RefSeq; XP_012337945.1; XM_012482522.1.
DR AlphaFoldDB; A0A0D9QEF4; -.
DR EnsemblProtists; KJP85445; KJP85445; AK88_04918.
DR GeneID; 24270232; -.
DR VEuPathDB; PlasmoDB:AK88_04918; -.
DR OMA; QKVTWIV; -.
DR OrthoDB; 169151at2759; -.
DR Proteomes; UP000054561; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR HAMAP; MF_03028; Pescadillo; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR010613; PES.
DR PANTHER; PTHR12221; PESCADILLO - RELATED; 1.
DR PANTHER; PTHR12221:SF6; PESCADILLO HOMOLOG; 1.
DR Pfam; PF06732; Pescadillo_N; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|HAMAP-Rule:MF_03028};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW Rule:MF_03028};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP-
KW Rule:MF_03028}.
FT DOMAIN 332..426
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 584..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..605
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 72339 MW; 04042EA7F604D363 CRC64;
MHIHKLRKKT KKKKEGKYFT KKSILKKLYL NDKEFQKLCI FKGIYPKDFK EIPVKLRRKF
YRQKVYYSKN DLNKLAHEKI IQDFRKIATC LKKYKKYKVA LEDQEKCKTL IKNFPKYALD
HIIKERFPVF SYAIEELDDA LSAVVAYSLL PSNENIGVLN RFVTNCEVIK NHFHHFIYKT
NRIKKGFISV KGYYLQAEIL QKKVTWLIPH TFTPYLDKTI DFSMITTFIE YYICLLKFVL
FKLYKMHNMT YPPEQSELLK NEQLRHLSYD EYLISLCKEK FGSSHGQVGE KNVLTLDGAH
PVVQSTQDGH HPNQREEEIE EIKHNIDEEN DTLKELFKNQ IYYIHTDMPL DILSLIILSC
GGSIGWNSPY SPYQLGDNNI THEILEPYGE GKQMEQQKFD RMYVQPQYIF DCLNRKKILP
CSDYSVDVTN LPVHLSPFIE DDNFKNFVKK EEYAINKLLN EEAEKNAQDT DAEETAKKYE
HGQANKDEDL LISDDELSKE KLQLLRNACL NNQMELEDED NYVPVRDETL KNNAQRVKEL
QAAQTTEHIQ RRKIALSKKK RKLYARIERA ERKQKMNIDK FINKARGKNL AGGAKKKKKK
NSSRAGSRRL YNN
//
