ID   A0A0D9QMI2_PLAFR        Unreviewed;       273 AA.
AC   A0A0D9QMI2;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Vacuolar iron transporter {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AK88_02282 {ECO:0000313|EMBL:KJP88007.1};
OS   Plasmodium fragile.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=5857 {ECO:0000313|EMBL:KJP88007.1, ECO:0000313|Proteomes:UP000054561};
RN   [1] {ECO:0000313|EMBL:KJP88007.1, ECO:0000313|Proteomes:UP000054561}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=nilgiri {ECO:0000313|Proteomes:UP000054561};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Duraisingh M., Young S.K., Zeng Q., Gargeya S., Abouelleil A.,
RA   Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Plasmodium fragile nilgiri.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CCC1 family.
CC       {ECO:0000256|ARBA:ARBA00007049}.
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DR   EMBL; KQ001666; KJP88007.1; -; Genomic_DNA.
DR   RefSeq; XP_012335336.1; XM_012479913.1.
DR   AlphaFoldDB; A0A0D9QMI2; -.
DR   EnsemblProtists; KJP88007; KJP88007; AK88_02282.
DR   GeneID; 24267596; -.
DR   VEuPathDB; PlasmoDB:AK88_02282; -.
DR   OMA; SRIGWLR; -.
DR   OrthoDB; 5485588at2759; -.
DR   Proteomes; UP000054561; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030026; P:intracellular manganese ion homeostasis; IEA:InterPro.
DR   CDD; cd02434; Nodulin-21_like_3; 1.
DR   InterPro; IPR008217; Ccc1_fam.
DR   PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR   PANTHER; PTHR31851:SF4; VACUOLAR IRON TRANSPORTER 1; 1.
DR   Pfam; PF01988; VIT1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        183..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        212..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        245..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   273 AA;  31147 MW;  C0F36302B5EE0F62 CRC64;
     MVSKKTLEAR KAFYNEDVEK SKEAHDSYHN LDTHGEQHSL DRDNLKTIIF GSLDGIITIF
     AIVSGCVGAK ITPAQVIIIG VGNLFANAIS MGFSEYTSTT AQRDFMLAER KREEWEIENC
     PSEEKQEMID IYMNKYKFDS EDARNLVEIT FRNKNFFLEH MMSEELGLII THEDKNESLK
     KGIIMFLSFC IFGMIPLFSY VAYTFFFEYT DYNTSFVVVF VSTLITLFIL GIFKSQFTNQ
     KPIHCALCMV LNGSIAGMVP FLLGILLKNN IAD
//