ID A0A0D9QV89_CHLSB Unreviewed; 442 AA.
AC A0A0D9QV89;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN Name=ACP7 {ECO:0000313|Ensembl:ENSCSAP00000000278.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000000278.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000000278.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000000278.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|RuleBase:RU361203}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AQIB01134632; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01134633; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01134634; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007994938.1; XM_007996747.1.
DR AlphaFoldDB; A0A0D9QV89; -.
DR STRING; 60711.ENSCSAP00000000278; -.
DR Ensembl; ENSCSAT00000001943.1; ENSCSAP00000000278.1; ENSCSAG00000003919.1.
DR eggNOG; KOG1378; Eukaryota.
DR GeneTree; ENSGT00390000015485; -.
DR OMA; QYIHRVW; -.
DR OrthoDB; 203742at2759; -.
DR BioGRID-ORCS; 103234653; 0 hits in 8 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 6.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR45867:SF3; ACID PHOSPHATASE TYPE 7; 1.
DR PANTHER; PTHR45867; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 28..442
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5005115451"
FT DOMAIN 36..128
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 139..341
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 366..427
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 442 AA; 50848 MW; 35A755F157C50620 CRC64;
MHPLPGYWSC CSLLLLFSLG VQEGVQGSPG APSAAPEQVH LSYPGEPGSM TVTWTTWVPT
RSEVQFGLQP TGPLPLRAQG TFVPFVDGGI LRRKLYIHRV TLRKLLPGVQ YVYRCGSAQG
WSRRFRFRAL KNGAHWSPRL AVFGDLGADN PKALPRLRRD TQQGMYDAVL HVGDFAYNMD
QDNARVGDRF MRLIEPVAAS LPYMTCPGNH EERYNFSNYK ARFSMPGDNE GLWYSWDLGP
AHIISFSTEV YFFLHYGRHL VQRQFRWLES DLQKANKNRA ARPWIITMGH RPMYCSNADL
DDCTRHESKV RRGLQGKLYG LEDLFYKYGV DLQLWAHEHS YERLWPIYNY QVFNGSEEMP
YTNPRGPVHI ITGSAGCEER LTPFAVFPRP WSAVRVKEYG YTRLHILNGT HIHIQQVSDD
QDGKIVDDVW VVRPLFGRRM YL
//
