ID A0A0D9R1V7_CHLSB Unreviewed; 632 AA.
AC A0A0D9R1V7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Unc-45 myosin chaperone B {ECO:0000313|Ensembl:ENSCSAP00000002596.1};
GN Name=UNC45B {ECO:0000313|Ensembl:ENSCSAP00000002596.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000002596.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000002596.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000002596.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region
CC {ECO:0000256|ARBA:ARBA00004556}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AQIB01146960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01146961; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01146962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9R1V7; -.
DR STRING; 60711.ENSCSAP00000002596; -.
DR Ensembl; ENSCSAT00000004342.1; ENSCSAP00000002596.1; ENSCSAG00000006303.1.
DR eggNOG; KOG4151; Eukaryota.
DR GeneTree; ENSGT00940000157654; -.
DR OMA; YEQATST; -.
DR Proteomes; UP000029965; Chromosome 16.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0051879; F:Hsp90 protein binding; IEA:Ensembl.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0061077; P:chaperone-mediated protein folding; IEA:Ensembl.
DR GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR024660; UCS_central_dom.
DR PANTHER; PTHR45994; FI21225P1; 1.
DR PANTHER; PTHR45994:SF2; PROTEIN UNC-45 HOMOLOG B; 1.
DR Pfam; PF11701; UNC45-central; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Myogenesis {ECO:0000256|ARBA:ARBA00022541};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 6..39
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 309..489
FT /note="UNC-45/Cro1/She4 central"
FT /evidence="ECO:0000259|Pfam:PF11701"
SQ SEQUENCE 632 AA; 70511 MW; 733EC3890C302960 CRC64;
MAEVEAVQLK EEGNRHFQLQ DYKAATKSYS QALKLTKDKA LLATLYRNRA ACGLKTESYV
QAASDASRAI DINSSDIKAL YRRCQALEHL GKLDQAFKDV QRCATLEPRN QNFQETLRRL
NTSIQEKLRV QFSTDLRVQK MFEILLDENS EADKREKAAN NLIVLGREEA GAEKIFQNNG
IALLLQLLDT KKPELVLAAV RTLSGMCSGH RARATVILHA VRIDRICSLM AVENEEMSLA
VCNLLQAIID SLSGEDKREH RGKEEALVLD TKKDLKQITS HLLDMLVSKK VSGQGRDQAL
NLLNKNVPRK DLAIHDNSRT IYVVDNGLRK ILKVVGQVPD LPSCLPLTDN TRMLASILIN
KLYDDLRCDP ERDHFRKICE EYITGKFDPQ DMDKNLNAIQ TVSGILQGPF DLGNQLLGLK
GVMEMMVALC GSERETDQLV AVEALIHAST KLSRATFIIT NGVSLLKQIY KTTKNEKIKI
RTLVGLCKLG SAGGTDYGLR QFAEGSTEKL AKQCRKWLCN TSIDTRTRRW AVEGLAYLTL
DADVKDDFVQ DIPALQAMFE LAKTSDKTIL YSVATTLVNC TNSYDVKEVI PELVQLAKFS
KQHVPEEHPK VGSGAMWEGY GLCHQASKGG GM
//
