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Database: UniProt
Entry: A0A0D9RF08_CHLSB
LinkDB: A0A0D9RF08_CHLSB
Original site: A0A0D9RF08_CHLSB 
ID   A0A0D9RF08_CHLSB        Unreviewed;      1871 AA.
AC   A0A0D9RF08;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   25-OCT-2017, entry version 13.
DE   SubName: Full=Transient receptor potential cation channel subfamily M member 7 {ECO:0000313|Ensembl:ENSCSAP00000007197};
GN   Name=TRPM7 {ECO:0000313|Ensembl:ENSCSAP00000007197};
OS   Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000007197, ECO:0000313|Proteomes:UP000029965};
RN   [1] {ECO:0000313|Ensembl:ENSCSAP00000007197, ECO:0000313|Proteomes:UP000029965}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAP00000007197}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2015) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCSAP00000007197}.
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DR   EMBL; AQIB01116059; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AQIB01116060; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSCSAT00000009065; ENSCSAP00000007197; ENSCSAG00000011086.
DR   GeneTree; ENSGT00760000119127; -.
DR   OMA; KQGPTNP; -.
DR   Proteomes; UP000029965; Chromosome 26.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0001726; C:ruffle; IEA:Ensembl.
DR   GO; GO:0003779; F:actin binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0017022; F:myosin binding; IEA:Ensembl.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0031032; P:actomyosin structure organization; IEA:Ensembl.
DR   GO; GO:0016340; P:calcium-dependent cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0010961; P:cellular magnesium ion homeostasis; IEA:InterPro.
DR   GO; GO:0070266; P:necroptotic process; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR   Gene3D; 1.20.5.1010; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR004166; MHCK_EF2_kinase.
DR   InterPro; IPR029601; TRPM7.
DR   InterPro; IPR032415; TRPM_tetra.
DR   InterPro; IPR037162; TRPM_tetra_sf.
DR   PANTHER; PTHR13800:SF8; PTHR13800:SF8; 1.
DR   Pfam; PF02816; Alpha_kinase; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF16519; TRPM_tetra; 1.
DR   SMART; SM00811; Alpha_kinase; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS51158; ALPHA_KINASE; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000029965};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    758    776       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    856    878       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    923    945       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    957    976       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    997   1016       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1078   1101       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN     1595   1830       Alpha-type protein kinase.
FT                                {ECO:0000259|PROSITE:PS51158}.
SQ   SEQUENCE   1871 AA;  213425 MW;  AEB4F30F0D537622 CRC64;
     SQKSWIESTL TKRECVYIIP SSKDPHRCLP GCQICQQLVR CFCGRLVKQH ACFTASLAMK
     YSDVKLGDHF NQAIEEWSVE KHTEQSPTDA YGVINFQGGS HSYRAKYVRL SYDTKPEVIL
     QLLLKEWQME LPKLVISVHG GMQKFELHPR IKQLLGKGLI KAAVTTGAWI LTGGVNTAGV
     AKHVGDALKE HASRSSRKIC TIGIAPWGVI ENRNDLVGRD VVAPYQTLLN PLSKLNVLNN
     LHSHFILVDD GTVGKYGAEV RLRRELEKTI NQQRIHARIG QGVPVVALIF EGGPNVILTV
     LEYLQESPPV PVVVCEGTGR AADLLAYIHK QTEEGGNLPD AAEPDIISTI KKTFNFGQNE
     AVHLFQTLME CMKRKELITV FHIGSDEHQD IDVAILTALL KGTNASAFDQ LILTLAWDRV
     DIAKNHVFVY GQQWLVGSLE QAMLDALVMD RVAFVKLLIE NGVSMHKFLT IPRLEELYNT
     KQGPTNPMLF HLVRDVKQGN LPPGYKITLI DIGLVIEYLM GGTYRCTYTR KRFRLIYNSL
     GGNNRRSGRN TSSSTPQLRK SHESFGNRAD KKEKMRHNHF IKTAQPYRPK IDTVVEEGKK
     KRTKDEIVDI DDPETKRFPY PLNELLIWAC LMKRQVMARF LWQHGEESMA KALVACKIYR
     SMAYEAKQSD LVDDTSEELK QYSNDFGQLA VELLEQSFRQ DETMAMKLLT YELKNWSNST
     CLKLAVSSRL RPFVAHTCTQ MLLSDMWMGR LNMRKNSWYK VILSILVPPA ILLLEYKTKA
     EMSHIPQSQD AHQMTMDDSE NNFQNITEEI PMEVFKEVRI LDSNEGKNEM EIQIKSKKLP
     ITRKFYAFYH APIVKFWFNT LAYLGFLMLY TFVVLVQMEQ LPSVQEWIVI AYIFTYAIEK
     VREIFMSEAG KVNQKIKVWF SDYFNISDTI AIISFFIGFG LRFGAKWNFA NAYDNHVFVA
     GRLIYCLNII FWYVRLLDFL AVNQQAGPYV MMIGKMVANM FYIVVIMALV LLSFGVPRKA
     ILYPHEAPSW TLAKDIVFHP YWMIFGEVYA YEIDVCANDS VIPQICGPGT WLTPFLQAVY
     LFVQYIIMVN LLIAFFNNVY LQVKAISNIV WKYQRYHFIM AYHEKPVLPP PLIILSHIVS
     LFCCICKRRK KDKTSDGPKL FLTEEDQKKL HDFEEQCVEM YFNEKDDKFH SGSEERIRVT
     FERVEQMCIQ IKEVGDRVNY IKRSLQSLDS QIGHLQDLSA LTVDTLKTLT AQKASEASKV
     HNEITRELSI SKHLAQNLID DGPVRPSVWK KHSVVNTLSS SVPQGDLESN NPFLCNILMK
     DDKDPQCNIF GQDLPAIPQR KEFNFPEAGS SSGALFPSAG SPPELRQRLH GVELLKIFNK
     NQKLGSSSNS IPHLSSPPTK FFVSTPSQPS CKSHLETGTK DQETVCSKAA EGDNIEFGAF
     VGHRDSMDLQ RFKETSNKIK EILFNNNTSE KTLKRVSSLA GFTDCHRTSI PLHSKQAEKI
     SRRPSTEDTH EVDSKAALIP DWLQDRPSNR EMPSEEGTLN GLTSPFKPAM DTNYYYSAVE
     RNNLMRLSQS IPFTPVPPRG EPVTVYRLEE SSPNILNNSM SSWSQLGLCA KIEFLSKEEM
     GGGLRRAVKV QCTWSEHDIL KSGHLYIIKS FLPEVVNTWS SIYKEDTVLH LCLREIQQQR
     AAQKLTFAFN QMKPKSIPYS PRRFLEVFLL YCHSAGQWFA VEECMTGEFR KYNNNNGDEI
     IPTNTLEEIM LAFSHWTYEY TRGELLVLDL QDIYKGVGEN LTDPSVIKAE EKRSCDMVFG
     PANLGEDAIK NFRAKHHCNS CCRKLKLPDL KRNDYTPDKI IFPQDEPSDL NLQPGNSTKE
     SESTNSVRLM L
//
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