ID A0A0D9RIR4_CHLSB Unreviewed; 524 AA.
AC A0A0D9RIR4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Polypyrimidine tract binding protein 3 {ECO:0000313|Ensembl:ENSCSAP00000008503.1};
GN Name=PTBP3 {ECO:0000313|Ensembl:ENSCSAP00000008503.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000008503.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000008503.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000008503.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01022354; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01022355; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01022356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01022357; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01022358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007966602.1; XM_007968411.1.
DR RefSeq; XP_007966604.1; XM_007968413.1.
DR AlphaFoldDB; A0A0D9RIR4; -.
DR SMR; A0A0D9RIR4; -.
DR STRING; 60711.ENSCSAP00000008503; -.
DR Ensembl; ENSCSAT00000010409.1; ENSCSAP00000008503.1; ENSCSAG00000012316.1.
DR GeneID; 103219009; -.
DR CTD; 9991; -.
DR eggNOG; KOG1190; Eukaryota.
DR GeneTree; ENSGT01050000244924; -.
DR OMA; NAHYARM; -.
DR OrthoDB; 4825346at2759; -.
DR BioGRID-ORCS; 103219009; 1 hit in 16 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 12.
DR Bgee; ENSCSAG00000012316; Expressed in blood and 7 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0033119; P:negative regulation of RNA splicing; IEA:Ensembl.
DR GO; GO:0045595; P:regulation of cell differentiation; IEA:InterPro.
DR CDD; cd12779; RRM1_ROD1; 1.
DR CDD; cd12693; RRM2_PTBP1_like; 1.
DR CDD; cd12703; RRM4_ROD1; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR033110; PTBP3_RRM4.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034326; ROD1_RRM1.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR PANTHER; PTHR15592:SF17; POLYPYRIMIDINE TRACT-BINDING PROTEIN 3; 1.
DR Pfam; PF13893; RRM_5; 2.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 31..115
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 154..230
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 330..404
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 447..522
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 524 AA; 56791 MW; A82C6B5E0CDC60A0 CRC64;
MNSSTPSAGV YANGNDSKKF KRDRPPCSPS RVLHLRKIPC DVTEAEIISL GLPFGKVTNL
LMLKGKSQAF LEMASEEAAV TMVNYYTPIT PHLRSQPVYI QYSNHRELKT DNLPNQARAQ
AALQAVSAVQ SGSLALSGGP SNEGTVLPGQ SPVLRIIIEN LFYPVTLEVL HQIFSKFGTV
LKIITFTKNN QFQALLQYAD PVNAHYAKMA LDGQNIYNAC CTLRIDFSKL TSLNVKYNND
KSRDFTRLDL PTGDGQPSLE PPMAAAFGAP GIISSPYAGA AGFAPAIGFP QATGLSVPAV
PGALGPLTIT SSAVTGRMAI PGASGIPGNS VLLVTNLNPD LITPHGLFIL FGVYGDVHRV
KIMFNKKENA LVQMADANQA QLAMNHLSGQ RLYGKVLRAT LSKHQAVQLP REGQEDQGLT
KDFSNSPLHR FKKPGSKNFQ NIFPPSATLH LSNIPPSVTV DDLKNLFIEA GCSVKAFKFF
QKDRKMALIQ LGSVEEAIQA LIELHNHDLG ENHHLRVSFS KSTI
//
