ID A0A0D9RIW0_CHLSB Unreviewed; 948 AA.
AC A0A0D9RIW0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Matrilin 2 {ECO:0000313|Ensembl:ENSCSAP00000008549.1};
GN Name=MATN2 {ECO:0000313|Ensembl:ENSCSAP00000008549.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000008549.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000008549.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000008549.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AQIB01087812; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01087813; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01087814; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01087815; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01087816; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01087817; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01087818; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01087819; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9RIW0; -.
DR STRING; 60711.ENSCSAP00000008549; -.
DR Ensembl; ENSCSAT00000010456.1; ENSCSAP00000008549.1; ENSCSAG00000012367.1.
DR eggNOG; KOG1217; Eukaryota.
DR GeneTree; ENSGT00940000158008; -.
DR OMA; CATEDHA; -.
DR Proteomes; UP000029965; Chromosome 8.
DR Bgee; ENSCSAG00000012367; Expressed in adrenal cortex and 5 other cell types or tissues.
DR GO; GO:0005604; C:basement membrane; IEA:Ensembl.
DR GO; GO:0120216; C:matrilin complex; IEA:Ensembl.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR GO; GO:0031104; P:dendrite regeneration; IEA:Ensembl.
DR GO; GO:0008347; P:glial cell migration; IEA:Ensembl.
DR GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd01475; vWA_Matrilin; 1.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 10.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF35; MATRILIN-2; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF14670; FXa_inhibition; 8.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 10.
DR SMART; SM00179; EGF_CA; 10.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS01186; EGF_2; 6.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..948
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002345462"
FT DOMAIN 57..236
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 361..401
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 655..830
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 948 AA; 105902 MW; 1A1BD0A31BE44A4D CRC64;
MEKMLAGCFL LFLGQILLLP AEARERSRGR SISRGRHART HPQTALLESS CENKRADLVF
IIDSSRSVNT HDYAKVKEFL MDILQFLDIG PDVTRVGLLQ YGSTVKNEFS LKTFKRKSEV
ERAVKRMRHL STGTMTGLAI QYALNIAFSE AEGARPLREN VPRVIMIVTD GRPQDSVAEV
AAKARDTGIL IFAIGVGQVD FNTLKAIGSE PHEDHVFLVA NFSQIETLTS VFQRKLCTAH
MCSTLEHNCA HFCINIPGSY VCRCKQGYIL NSDQTTCRIQ DLCAMEDHNC GQLCVNVPGS
FVCQCYSGYA LAEDGKSCVA VDYCASENHG CEHECVNADG SYLCQCHEGF ALNPDKKTCT
KIDYCASSNH GCQHECVNTD DSYSCRCLKG FTLNPDKKTC RRINYCALNK PGCEHECINT
EESYYCRCRR GYTLDPNGKT CSRVDHCAQQ DHGCEQLCLN TEESFVCQCS EGFLINEDLK
TCSRVDYCLL SDHGCEYSCV NVDRSFACQC PEGHVLRSDG KTCAKLDSCA LGDHGCEHLC
VSSEDSYVCQ CFEGYVLRED GKTCRRKDVC QAVDHGCEHI CVNSDDSYTC KCLEGFRLAQ
DGKRCQRKDV CKSTHHGCEH ICVNNGISYI CKCSEGFVLA EDGRRCKKCT EGPIDLVFVI
DGSKSLGEEN FEVVKQFVTG IIDSLTISPK AARVGLLQYS TQVRTEFTLR NFNSAKDMKK
AVAHMKYMGK GSMTGLALKH MFERSFTQGE GARPLSTRVP RAAIVFTDGR AQDDVSEWAS
KAKANGITMY AVGVGKAIEE ELQEIASEPT DKHLFYAEDF STMDEISEKL KKGICEALED
SDGRQDSPAG ELPKRVQQPT VQHRYLFEED NLLRSTQKLS HSTKPSGSPL EEKHDQCKCE
NLIMFQNLAN EEVRKLTQRY ILFLYYASVW NAKNIIKTSH TLYVGFIN
//
