ID A0A0D9RVA5_CHLSB Unreviewed; 216 AA.
AC A0A0D9RVA5;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=RAB2B, member RAS oncogene family {ECO:0000313|Ensembl:ENSCSAP00000012544.1};
GN Name=RAB2B {ECO:0000313|Ensembl:ENSCSAP00000012544.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000012544.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000012544.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000012544.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
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DR EMBL; AQIB01128652; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01128653; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01128654; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007988946.1; XM_007990755.1.
DR AlphaFoldDB; A0A0D9RVA5; -.
DR SMR; A0A0D9RVA5; -.
DR STRING; 60711.ENSCSAP00000012544; -.
DR Ensembl; ENSCSAT00000014575.1; ENSCSAP00000012544.1; ENSCSAG00000016480.1.
DR GeneID; 103231391; -.
DR KEGG; csab:103231391; -.
DR CTD; 84932; -.
DR eggNOG; KOG0098; Eukaryota.
DR GeneTree; ENSGT00940000153886; -.
DR OMA; RRETFIH; -.
DR OrthoDB; 4819304at2759; -.
DR BioGRID-ORCS; 103231391; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 29.
DR Bgee; ENSCSAG00000016480; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0001669; C:acrosomal vesicle; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR GO; GO:0045921; P:positive regulation of exocytosis; IEA:Ensembl.
DR GO; GO:0032481; P:positive regulation of type I interferon production; IEA:Ensembl.
DR CDD; cd01866; Rab2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47979; DRAB11-RELATED; 1.
DR PANTHER; PTHR47979:SF50; RAS-RELATED PROTEIN RAB-2B; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT REGION 189..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 216 AA; 24200 MW; 43A73F6D259701CA CRC64;
MTYAYLFKYI IIGDTGVGKS CLLLQFTDKR FQPVHDLTIG VEFGARMVNI DGKQIKLQIW
DTAGQESFRS ITRSYYRGAA GALLVYDITR RETFNHLTSW LEDARQHSSS NMVIMLIGNK
SDLESRRDVK REEGEAFARE HGLIFMETSA KTACNVEEAF INTAKEIYRK IQQGLFDVHN
EANGIKIGPQ QSISTSVGPS ASQRNSRDVG SNSGCC
//
