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Database: UniProt
Entry: A0A0D9RY30_CHLSB
LinkDB: A0A0D9RY30_CHLSB
Original site: A0A0D9RY30_CHLSB 
ID   A0A0D9RY30_CHLSB        Unreviewed;      1813 AA.
AC   A0A0D9RY30;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   30-AUG-2017, entry version 17.
DE   SubName: Full=Sodium leak channel, non-selective {ECO:0000313|Ensembl:ENSCSAP00000013519};
GN   Name=NALCN {ECO:0000313|Ensembl:ENSCSAP00000013519};
OS   Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000013519, ECO:0000313|Proteomes:UP000029965};
RN   [1] {ECO:0000313|Ensembl:ENSCSAP00000013519, ECO:0000313|Proteomes:UP000029965}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAP00000013519}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2015) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCSAP00000013519}.
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DR   EMBL; AQIB01099479; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AQIB01099480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSCSAT00000015582; ENSCSAP00000013519; ENSCSAG00000017489.
DR   GeneTree; ENSGT00830000128247; -.
DR   OMA; MLGDSAM; -.
DR   Proteomes; UP000029965; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005261; F:cation channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028823; NALCN.
DR   PANTHER; PTHR10037:SF252; PTHR10037:SF252; 1.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029965};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     87    107       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    113    134       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    154    173       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    185    204       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    224    241       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    345    368       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    431    452       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    464    492       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    552    574       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    621    645       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    956    980       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1031   1049       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1092   1115       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1209   1232       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1286   1306       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1312   1331       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1351   1369       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1411   1433       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1498   1522       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       82    377       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      430    649       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      962   1237       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1284   1532       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      873    902       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1813 AA;  208999 MW;  5344F4F316A87B7D CRC64;
     MYALQIHRYM WGTQFFDERK NSLDDKYTFS FSQTVVLCLL TKANLSMLKR KQSSRVEAQP
     VADFGPDESL SDNADILWIN KPWVHSLLRI CAIISVISVC MNTPMTFEHY PPLQYVTFTL
     DTLLMFLYTA EMIAKMHIRG IVKGDSSYVK DRWCVFDGFM VFCLWVSLVL QVFEIADIVD
     QMSPWGMLRI PRPLIMIRAF RIYFRFELPR TRITNILKRS GEQIWSVSIF LLFFLLLYGI
     LGVQMFGTFT YHCVVNDTKP GNVTWNSLAI PDTHCSPELE EGYQCPPGFK CMDLEDLGLS
     RQELGYSGFN EIGTSIFTVY EAASQEGWVF LMYRAIDSFP RWRSYFYFIT LIFFLAWLVK
     NVFIAVIIET FAEIRVQFQQ MWGSRSSTTS TATTQMFHED AAGGWQLVAV DVNKPQGRAP
     ACLQKMMRSS VFHMFILSMV TVDVIVAASN YYKGENFRRQ YDEFYLAEVA FTVLFDLEAL
     LKIWCLGFTG YISSSLHKFE LLLVIGTTLH VYPDLYHSQF TYFQVLRVVR LIKISPALED
     FVYKIFGPGK KLGSLVVFTA SLLIVMSAIS LQMFCFVEEL DRFTTFPRAF MSMFQILTQE
     GWVDVMDQTL NAVGHMWAPV VAIYFILYHL FATLILLSLF VAVILDNLEL DEDLKKLKQL
     KQSEANADTK EKLPLRLRIF EKFPNRPQMV KISKLPSDFT VPKIRESFMK QFIDRQQQDT
     CCLLRSLPST SSSSCDHSKR SAIEDNKYID QKLRKSVFSI RARNLLEKET AVTKILSKRP
     LPTRSPISIR CCLYLGRSHC HSSGVRACTR QRMLSGSFEG QPAKERSILS VQHHIRQERR
     SLRHGSNSQR ISRGKSLETL TQDHSNTVRY RNAQREDSEI KMIQEKKEQA EMKRKVQEEE
     LRENHPYFDK PLFIVGREHR FRNFCRVVVR ARFNASKTDP VTGAVKNTKY HQLYDLLGLV
     TYLDWVMIIV TICSCISMMF ESPFRRVMHA PTLQIAEYVF VIFMSIELNL KIMADGLFFT
     PTAVIRDFGG VMDIFIYLVS LIFLCWMPQN VPAESGAQLL MVLRCLRPLR IFKLVPQMRK
     VVRELFSGFK EIFLVSILLL TLMLVFASFG VQLFAGKLAK CNDPNIIRRE DCNGIFRINV
     SVSKNLNLKL RPGEKKPGFW VPRVWANPRN FNFDNVGNAM LALFEVLSLK GWVEVRDVII
     HRVGPIHGIY IHVFVFLGCM IGLTLFVGVV IANFNENKGT ALLTVDQRRW EDLKSRLKIA
     QPLHLPPRPD NDGFRAKMYD ITQHPFFKRT IALLVLAQSV LLSVKWDVED PVTVPLATMS
     VVFTFIFVLE VTMKIIAMSP AGFWQSRRNR YDLLVTSLGV VWVVLHFALL NAYTYMMGAC
     VIVFRFFSIC GKHVTLKMLL LTVVVSMYKS FFIIVGMFLL LLCYAFAGVV LFGTVKYGEN
     INRHANFSSA GKAITVLFRI VTGEDWNKIM HDCMVQPPFC TPDEFTYWAT DCGNYAGALM
     YFCSFYVIIA YIMLNLLVAI IVENFSLFYS TEEDQLLSYN DLRHFQIIWN MVDDKREGVI
     PTFRVKFLLR LLRGRLEVDL DKDKLLFKHM CYEMERLHNG GDVTFHDVLS MLSYRSVDIR
     KSLQLEELLA REQLEYTIEE EVAKQTIRMW LKKCLKRIRA KQQQSCSIIH SLRESQQQEL
     SRFLNPPSIE TTQPSEDTNA NSQDNSMQPE TSSQQQLLSP TLSDRGGSRQ DAADAGKPQR
     KFGQWRLPSA PKPISHSVSS VNLRFGGRTT MKSVVCKMNP MTDAASCGSE VKKWWTRQLT
     VEXDESGDDL LDI
//
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