ID   A0A0D9S632_CHLSB        Unreviewed;      1035 AA.
AC   A0A0D9S632;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=NLR family pyrin domain containing 11 {ECO:0000313|Ensembl:ENSCSAP00000016321.1};
GN   Name=NLRP11 {ECO:0000313|Ensembl:ENSCSAP00000016321.1};
OS   Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000016321.1, ECO:0000313|Proteomes:UP000029965};
RN   [1] {ECO:0000313|Ensembl:ENSCSAP00000016321.1, ECO:0000313|Proteomes:UP000029965}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAP00000016321.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NLRP family.
CC       {ECO:0000256|ARBA:ARBA00008665}.
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DR   EMBL; AQIB01135252; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AQIB01135253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A0D9S632; -.
DR   STRING; 60711.ENSCSAP00000016321; -.
DR   Ensembl; ENSCSAT00000016822.1; ENSCSAP00000016321.1; ENSCSAG00000001707.1.
DR   eggNOG; ENOG502QQ5H; Eukaryota.
DR   GeneTree; ENSGT00940000163635; -.
DR   OMA; MDTLWEL; -.
DR   OrthoDB; 5259946at2759; -.
DR   Proteomes; UP000029965; Chromosome 6.
DR   CDD; cd08320; Pyrin_NALPs; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR004020; DAPIN.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR45690:SF5; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 11; 1.
DR   PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF02758; PYRIN; 1.
DR   SMART; SM00368; LRR_RI; 9.
DR   SMART; SM01289; PYRIN; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50824; DAPIN; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   3: Inferred from homology;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT   DOMAIN          1..98
FT                   /note="Pyrin"
FT                   /evidence="ECO:0000259|PROSITE:PS50824"
FT   DOMAIN          149..281
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   1035 AA;  117923 MW;  945CB524A9FDE680 CRC64;
     MAESNSTDFD LLWYLENLSD KEFQSFKKYL ARKILDFKLP QVPLINLRAT KEELANLLPI
     SYEGQHIWNM LYSIFLMMRK EDHCMKIIGR RNRNQEACKA LMRRKITLRW ENHTFGEFHY
     KFFCNVASDV FYVLQLAYDS TSCYSASDLN VFLMGDRACG KTMTINLAVM KWINGEMWQN
     MISYIVHLTS HEINQMTDSS LAELIAKDWP DGQAPIADIL SDPKKLLFIL EDVDNLRFEL
     NVNEHALCSN STQKVPIPIL LVSLLKRQMA PGCWFLISSR PTREENIKMF LKTTDCYVTL
     QFSNEKRELY FHSFFNDRQR ASTALMLVHD NEILTGLCRV AILCWITCTV LNRQMDKGHD
     PQHCCETPTD LHAHFLADAL TSKAGLTANQ YHLGLLQRLC LLAAAGLFLS TLNFSGEDLR
     CVGFTETDVS VLQAVNILLP SSTHKDRYKF IHLNVQEFCA AVAFLMAVPN CLIPSGSRGY
     KEKREQYCNF NQVFTFIFGL LNENRRKILE TTFGYQLPMV DSFRRYSVEY MKHLGRDQEK
     LTHHGSLFYC LFENQEEEFV KKVANTLKEV TVYLQSNKDM MVSLYCLEYC CHLRTFKLSV
     QRIFEYKEPL VRPTASQMKS LVYWREICSL FCTMDTLWEL HLFDSDLNDI SERILSKALE
     HSSCKLRTLK LSYISTASGF EDLLKALARN RSLIHLSLNC TSISLNMFSL LREILDKSTC
     QISHLSLMKC DLGASKCGEI ASLLVSGGSL RKLTLTNNPL RNDGVNILCN ALLHPNCTLT
     SLALVFCCLT EKCCSSLGRV LLLGRTLKQL DLCVNHLQNY GVLHVTFPLI FPTCQLEELY
     LSGCFFTNDI CQYIAIVIAT NETLRSLEIG SNSIEDAGMQ LLCGGLRHPD CMLVNIGLEE
     CMLTGACCES LASVLTTNKT LERLNILKNQ LGDEGVVKLL ESLILPECGL QIIGLPLNDV
     SAETRRMVMT VKERKPNLIF LSETWSVKEG REIGVIPASQ PGSVIPNSNL DYMFFKFPRM
     STPMGMSNTA SRQPL
//