ID A0A0D9SDU2_CHLSB Unreviewed; 350 AA.
AC A0A0D9SDU2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Transcription elongation factor A N-terminal and central domain containing {ECO:0000313|Ensembl:ENSCSAP00000019031.1};
GN Name=TCEANC {ECO:0000313|Ensembl:ENSCSAP00000019031.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000019031.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000019031.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000019031.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
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DR EMBL; AQIB01143495; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007989241.1; XM_007991050.1.
DR RefSeq; XP_007989242.1; XM_007991051.1.
DR AlphaFoldDB; A0A0D9SDU2; -.
DR STRING; 60711.ENSCSAP00000019031; -.
DR Ensembl; ENSCSAT00000019622.1; ENSCSAP00000019031.1; ENSCSAG00000019532.1.
DR GeneID; 103231614; -.
DR KEGG; csab:103231614; -.
DR CTD; 170082; -.
DR eggNOG; KOG1105; Eukaryota.
DR GeneTree; ENSGT00940000162067; -.
DR OMA; FNCKVTV; -.
DR OrthoDB; 1383197at2759; -.
DR BioGRID-ORCS; 103231614; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome X.
DR Bgee; ENSCSAG00000019532; Expressed in fibroblast and 4 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.20.25.10; -; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR InterPro; IPR035100; TF_IIS-typ.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR11477:SF7; TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08711; Med26; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR PIRSF; PIRSF006704; TF_IIS; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 5..82
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT DOMAIN 172..288
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 88..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 40065 MW; 1421AC28A2CCCD10 CRC64;
MSDKNQIAAR ASLIEQLMSK RNFEDLGNHL TELETIYVTK EHLQETDVVR TVYRVLKNCP
SVALKNKAKC LLSKWKAVYK ETHSKARNSP KLFPVRGNEE NSGPSHDPSQ DETLGICSSN
SLSSQDVAKL SEMIVPENRA IQLKPKKEHF GDSGPESTGK RLSELLDPTT PMRTKCIELL
YAALTSSSAD QPKADLWQNF AREIEEHVFT LYSKNIKKYK TCIRSKVANL KNPKNSHLQQ
NLLSGTMSPR EFAEMTVMEM ANKELKQLRA SYTESCIQEH YLPQVIDGTQ TNKIKCRRCE
KYNCKVTVID RGTLFLPSWV RNSNPDEQMM TYVICNECGE QWYHSKWVCF
//
