ID A0A0D9SE86_CHLSB Unreviewed; 423 AA.
AC A0A0D9SE86;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Torsin family 4 member A {ECO:0000313|Ensembl:ENSCSAP00000019175.1};
GN Name=TOR4A {ECO:0000313|Ensembl:ENSCSAP00000019175.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000019175.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000019175.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000019175.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family. Torsin subfamily.
CC {ECO:0000256|ARBA:ARBA00006235}.
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DR EMBL; AQIB01148178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008003675.1; XM_008005484.1.
DR AlphaFoldDB; A0A0D9SE86; -.
DR STRING; 60711.ENSCSAP00000019175; -.
DR Ensembl; ENSCSAT00000019769.1; ENSCSAP00000019175.1; ENSCSAG00000019679.1.
DR GeneID; 103239562; -.
DR KEGG; csab:103239562; -.
DR CTD; 54863; -.
DR eggNOG; KOG2170; Eukaryota.
DR GeneTree; ENSGT00950000182888; -.
DR OMA; CFQILNA; -.
DR OrthoDB; 3074968at2759; -.
DR BioGRID-ORCS; 103239562; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 12.
DR Bgee; ENSCSAG00000019679; Expressed in caudate nucleus and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010448; Torsin.
DR PANTHER; PTHR10760; TORSIN; 1.
DR PANTHER; PTHR10760:SF1; TORSIN-4A; 1.
DR Pfam; PF06309; Torsin; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 186..344
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 50..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 46819 MW; 35A5E9737F10B921 CRC64;
MDRGQPSLEP AAAAPQATGR CVIAPVRAVL RLRRRVCVLR KRRLLQLGGG PDVGTGVPRP
GCSPPAPRGD LDQPQFFTFD GPAELPSRTP RKKRRRSRVV LYPETSRKYR PRVEHRSRAQ
HCLLLLVAIV GFQVLNAIEN LDDNAQRYDL DGLEKALQRA VFGQPAAIAR IVALMRDYLA
THVHSRPLLL ALHGPSGVGK SHVGRLLARH FRSVLEDSSL VLQYHARHHC PEARAAQDCR
EELARRVADV VARAEAEEKT PLLVLDDVEL LPRPLLDELH GFLQPQRSHH FHNAIYVLLS
GAGGAEVTRF VLQNASRALP LLPDGARSAE ASAAQAEEDL RTSLWALLSR EHPLWQAAAI
VPFLLLDKRD VVSCFRDEMA GEGFFPDQAR AEDLAAQLSF YRVAGREFAV TGCKQVVATV
NLL
//
