ID   A0A0E0KAC2_ORYPU        Unreviewed;       941 AA.
AC   A0A0E0KAC2;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   RecName: Full=methionine--tRNA ligase {ECO:0000256|ARBA:ARBA00012838};
DE            EC=6.1.1.10 {ECO:0000256|ARBA:ARBA00012838};
OS   Oryza punctata (Red rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4537 {ECO:0000313|EnsemblPlants:OPUNC03G07600.1};
RN   [1] {ECO:0000313|EnsemblPlants:OPUNC03G07600.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wing R.;
RT   "Oryza genome evolution.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:OPUNC03G07600.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (APR-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|RuleBase:RU363039}.
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DR   AlphaFoldDB; A0A0E0KAC2; -.
DR   STRING; 4537.A0A0E0KAC2; -.
DR   EnsemblPlants; OPUNC03G07600.1; OPUNC03G07600.1; OPUNC03G07600.
DR   Gramene; OPUNC03G07600.1; OPUNC03G07600.1; OPUNC03G07600.
DR   eggNOG; KOG0436; Eukaryota.
DR   HOGENOM; CLU_013790_0_0_1; -.
DR   Proteomes; UP000026962; Chromosome 3.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004825; F:methionine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd07957; Anticodon_Ia_Met; 1.
DR   CDD; cd00814; MetRS_core; 1.
DR   Gene3D; 2.170.220.10; -; 1.
DR   Gene3D; 3.40.50.620; HUPs; 3.
DR   InterPro; IPR041872; Anticodon_Met.
DR   InterPro; IPR014758; Met-tRNA_synth.
DR   InterPro; IPR023457; Met-tRNA_synth_2.
DR   InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR   InterPro; IPR033911; MetRS_core.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR   NCBIfam; TIGR00398; metG; 1.
DR   PANTHER; PTHR43326:SF1; METHIONINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43326; METHIONYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF19303; Anticodon_3; 1.
DR   Pfam; PF09334; tRNA-synt_1g; 4.
DR   SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 2.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363039};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363039};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363039};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363039};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363039};
KW   Reference proteome {ECO:0000313|Proteomes:UP000026962}.
FT   DOMAIN          78..125
FT                   /note="Methionyl/Leucyl tRNA synthetase"
FT                   /evidence="ECO:0000259|Pfam:PF09334"
FT   DOMAIN          126..231
FT                   /note="Methionyl/Leucyl tRNA synthetase"
FT                   /evidence="ECO:0000259|Pfam:PF09334"
FT   DOMAIN          232..336
FT                   /note="Methionyl/Leucyl tRNA synthetase"
FT                   /evidence="ECO:0000259|Pfam:PF09334"
FT   DOMAIN          449..542
FT                   /note="Methionyl/Leucyl tRNA synthetase"
FT                   /evidence="ECO:0000259|Pfam:PF09334"
FT   DOMAIN          565..699
FT                   /note="Methionyl-tRNA synthetase anticodon-binding"
FT                   /evidence="ECO:0000259|Pfam:PF19303"
FT   REGION          692..761
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        692..707
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        708..724
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   941 AA;  104551 MW;  7516DA889FAE0498 CRC64;
     MAAGRAFLRA APSSLAAGAG RFAFACPMAL PLLAAAAAGP HRRGRGRGRC YCSASDAARP
     YVLTTPLYYV NAPPHMGNIE YDKFIRTTDP KHDAVVNDFY SRVLDSGDIY RADYEGLYCV
     SCEEYKVQGW VKSGLRDFSI SRASVEWGIP VPNDTKQTIY VWFDALLGYI SALLDDGEKA
     SLQQAVERGW PASVHLIGKD ILRFHAVYWP AMLMSAGISV PDAVFGHGFL TKRLLDKRVV
     FITGTDEHGE KIATSAEACG RNPKDHCDTI SNSYKMLWAD LDIEYDKFIR TTDPKHDAVV
     NDFYSRVLDS GDIYRADYEG LYCVSCEEYK DEKELGENKC CPVHLKPCVP RKEDNYFFAL
     SKYQHQLEDL LTKNPNFVRP SHRLNEVQGW VKSGLRDFSI SRASVEWGIP VPNDTKQTIY
     VWFDALLGYI SALLDDGEKA SLQQAVERVY WPAMLMSAGI SVPDAVFGHG FLTKDGMKMG
     KSLGNTLEPK DLVNRFGVDA VRYFFLREVE FGNDGDYSEE RFINIVNAHL ANTIGNLLNR
     TLGLLKKNCK STLAFDSIAA ADGISLKDNV ENLVDKAKDQ FENLLLSSAC ETLMEIGNLG
     NLYIDEQAPW SCFKQGGESA EKAAKDLVII LETMRIIAIA LSPITPSLSL RIYTQLGFTE
     DQFRTLRWED TKWGGLKAGQ VMMEPKPVFA RLETETDEKD QSSSKPTKGG KKKARTKLHR
     LPLPLRRRSG GTAMSSVSDP QANGDHQPAA EAEMEDNGAQ VEEVADSVET MEGVASIALL
     PSGAISGHFI RLPDSVCYGL HGTPISCERE CSRGEDYRLI KLSIIDFKNK REKVVVVECR
     GHDAARLQNI DHLHGWEDDI VGLVEKKHGN QKFSLSFECE TLKADKAAEE HISKYMPNLR
     GLDAIVNIGK MSISGINLDK DDEPSENAAI LQEHLMYGAL A
//