ID A0A0E0LKV2_ORYPU Unreviewed; 1141 AA.
AC A0A0E0LKV2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
OS Oryza punctata (Red rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4537 {ECO:0000313|EnsemblPlants:OPUNC07G13770.1};
RN [1] {ECO:0000313|EnsemblPlants:OPUNC07G13770.1}
RP NUCLEOTIDE SEQUENCE.
RA Wing R.;
RT "Oryza genome evolution.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:OPUNC07G13770.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A0E0LKV2; -.
DR STRING; 4537.A0A0E0LKV2; -.
DR EnsemblPlants; OPUNC07G13770.1; OPUNC07G13770.1; OPUNC07G13770.
DR Gramene; OPUNC07G13770.1; OPUNC07G13770.1; OPUNC07G13770.
DR eggNOG; KOG2108; Eukaryota.
DR HOGENOM; CLU_004585_0_1_1; -.
DR OMA; FILYVMM; -.
DR Proteomes; UP000026962; Chromosome 7.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:EnsemblPlants.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:EnsemblPlants.
DR GO; GO:0036292; P:DNA rewinding; IEA:EnsemblPlants.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF61; DNA HELICASE; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000026962}.
FT DOMAIN 288..580
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 581..892
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..44
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..167
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 309..316
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1141 AA; 127971 MW; 982E676B4D977DFC CRC64;
MSRWKENASP LPLHPGGSSS LLPRKRPPPS PPPPQPPCPP PRRPLADVTG NALRQRGSGG
GGFGHGYSTP ASKAPRSSCG FLLDDDDEGM DEAFLREVDA MCEEHERSSA RKDKEAGEAP
PSIPSEPESG VSGDAFRKEG NAICDEDDAQ PVGMSQEEME EVDEEEISEL WFGDDSLPPA
ISIATEGGEQ FEDAFWNVND ISEEVHHTDS STKCQEDMDK KNSDDPSVPS VICHEEGEGK
LVDEFLEDVD AIHQSDATKG QDEPQETELE IEENEGCVPK KYYDYLQSLN DRQREAACSD
VTIPLMIVAG PGSGKTSTMV GRVLTLLKEE IPPSNILAMT FTTAAASEMR DRIGTVVGKA
VAKEIVISTF HSFCLQLCRT HAEKLGRTSE FIIYGNGQQR RAVIEAERLL ESDKNNSLGD
ANMNYDGDIK NSFKDKAKKW QKFVTQAKAS GRTPEEYEKK GDLTGASILR HYNEILRSCN
ALDYHDFINS SITLLTKFPE VYDECRNTWQ AIVVDEFQDT SAMQYYLLKT LASHNRITIV
GDEDQSIFSF NGADVSGFDS FRRDFPNHKE VRLSKNYRST RAIVEAATAL IHNNTKRQSH
KLVETDNPSG NKIIVKECHS EDSQCAFVID KIIEITSSSV EGCHFGKIAV LYRRQITGKT
FQASFRNRKI PFNVHGVAFY RKKVIKAIMA ILKTTLPGCD DDVPWHQAFK AILPGDKEEK
KKIIHHIEKI SLARKCSFIW AATDIFSAKV SGTFKRAQIT QGRKVLSALD SLSKLVEREQ
SVSVVISSAG DMLPQKYLLE KRAIVDADGG KLLNEDNDIR SVLQFLMDDV SDFLSTHFSS
SVETSKTEEK GCASTLKAFI DYISLRETEN FRSRKEENKN SITLTTIHQS KGLEWDVVFI
VQANDSEIPL LHEYNGTVKE AGSTLEEERR LFYVAMARAR KKLYILHVTL LQPSRFLREI
PAHLLEVQGE GTVRKTPEQP LNIPFDQPEG DTSVEKSMAV QNETSPFLEM DQPCLANDFL
KRFEIEDRAI VSHIFHQWAK KQAFQNPKRL LDKIGFVIDE RVRGKGYKRK DVLCKLKSFL
SGDEAFGYAQ YEHFQKQRIE NSMGSSEPTP KQISYLRNLG CTITPTSRLH ASHLIEKYKS
L
//
