ID A0A0E0PDS3_ORYRU Unreviewed; 1221 AA.
AC A0A0E0PDS3;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=DNA ligase IV {ECO:0000256|ARBA:ARBA00031942};
DE AltName: Full=Polydeoxyribonucleotide synthase [ATP] 4 {ECO:0000256|ARBA:ARBA00030676};
OS Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI04G26210.4, ECO:0000313|Proteomes:UP000008022};
RN [1] {ECO:0000313|Proteomes:UP000008022}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA Zhao Q.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORUFI04G26210.4}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC {ECO:0000256|ARBA:ARBA00007572}.
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DR AlphaFoldDB; A0A0E0PDS3; -.
DR EnsemblPlants; ORUFI04G26210.4; ORUFI04G26210.4; ORUFI04G26210.
DR Gramene; ORUFI04G26210.4; ORUFI04G26210.4; ORUFI04G26210.
DR Proteomes; UP000008022; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd07903; Adenylation_DNA_ligase_IV; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 2.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR044125; Adenylation_DNA_ligase_IV.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR021536; DNA_ligase_IV_dom.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR029710; LIG4.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR45997; DNA LIGASE 4; 1.
DR PANTHER; PTHR45997:SF1; DNA LIGASE 4; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 2.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR Pfam; PF11411; DNA_ligase_IV; 1.
DR SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50172; BRCT; 2.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS00333; DNA_LIGASE_A2; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 327..467
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
FT DOMAIN 617..705
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 724..834
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 844..1111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1143..1209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 844..869
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 903..951
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 961..1007
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1020..1060
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1075..1092
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1152..1195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1221 AA; 137374 MW; C782A5AECE9E14EA CRC64;
MAATVRFGLL VAMFQAMSRD RTAAKKRARL RALLDRAYGP GGRDDYFSAL RLVLPGLDRE
RGSYGLKEAA LASVLVDALG IAKDSPDAVR LTNWRRGGGF RNAGNFALVA AEVLQRRQGM
TSGGLTIKEV NDALDRLAAT ENRSEKASIL SSLIKKTNAL EMKWLLMIIL KDLKLGISEK
SVFHEFHPDA EDLFNVTCDL RLVCEKLNDR SQRHKRQDIE VGKAVRPQLS MRVNNASSAW
KKLHGKQVVA ECKFDGDRIQ IHKNGEEIHF FSRICTWNVQ TKAAKEGLET DRQLCCILEW
IASYVLALCV NILSCQDFFF SNKRESYVAF DILYAGDTSV IHQSLTERHE ILQKVVRPLK
GHLEILVPTG GLNIHRPPDE PCWSILAHSL DDVEKFFKDT VDNREEGIIL KDLESKWEPG
DRSGKWLKLK PDYIHAGADL DVIIIGGYYG SGRRGGEVAQ FLVGLAVPSD DNSYPKRFLS
FCRVGTGLSD EELDALVTKL KPHFRKNEYP KKPPRFYEVT NHSKERPDVW IESPDNLRFP
RIQRLRYDKP WHECLDVQAF VDIVHSSNGT THRAADDDND LKNVKVKQPR TNKKGEKKNV
SIIPSHLMKT DISGLKGETL IFANTMFYFV NIPPSYNLDY FHKLVVENGG SFSMNLNDSV
THCIAAEKKD FARHKFPEEI DSYADYFYWD IDISDLKQIF SNMDRAVVDS NMVHHYKKKY
CADERFCFFQ GCCVYFYHAP LVNADYNVIS DLALKRVKQD LTMHGGQVCS ILAPATHLII
VSVLQAYNFD MLYKSLPPAE RRYLHDKRLQ VVSNKWLEDS VEKQTRLPET TYSLKPDTLE
EIEIERSEET VQPCNDKLEE NEKADTSHVK HAPRKRGRPS SSASRTAKPA PRPVRRTRAR
RGNQHAKIDD VEPEESDHGE TGLDDQIPDT DNISKMEVDS FDKDQVSARP VRRTRARRGK
QHAKIDYGQS EESDPGETGQ DDQRLDADYI SKMEEDSSDR DQGAHPTAPR VVRRSRAQRG
KWLAKIDRET GPGETGQDDK KLNADSISKM EEHAHDKDQE PPPGAQLITL DEQEPKGIKS
STTETPSSPK HERNQTVLRR DTAETTSSAT CEKMEQMVDP LHAMLLDMIP SLGQMKTDVG
NRVAEAKAET NPPWVGSSTS SYVAPVPQAS ASSASSSGVP APHAGSSTQS TGVPAPDPTA
GAPKKKKVSY KDVAGALLKD W
//
