ID   A0A0E0PGE1_ORYRU        Unreviewed;      1213 AA.
AC   A0A0E0PGE1;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=methionine S-methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00888};
DE            EC=2.1.1.12 {ECO:0000256|PROSITE-ProRule:PRU00888};
OS   Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI05G00350.1, ECO:0000313|Proteomes:UP000008022};
RN   [1] {ECO:0000313|Proteomes:UP000008022}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA   Zhao Q.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORUFI05G00350.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-methionine + S-adenosyl-L-methionine = S-adenosyl-L-
CC         homocysteine + S-methyl-L-methionine; Xref=Rhea:RHEA:13761,
CC         ChEBI:CHEBI:57844, ChEBI:CHEBI:57856, ChEBI:CHEBI:58252,
CC         ChEBI:CHEBI:59789; EC=2.1.1.12; Evidence={ECO:0000256|PROSITE-
CC         ProRule:PRU00888};
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. {ECO:0000256|PROSITE-ProRule:PRU00888}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A0E0PGE1; -.
DR   STRING; 4529.A0A0E0PGE1; -.
DR   EnsemblPlants; ORUFI05G00350.1; ORUFI05G00350.1; ORUFI05G00350.
DR   Gramene; ORUFI05G00350.1; ORUFI05G00350.1; ORUFI05G00350.
DR   eggNOG; ENOG502QS81; Eukaryota.
DR   HOGENOM; CLU_005080_0_0_1; -.
DR   OMA; LGANGHY; -.
DR   Proteomes; UP000008022; Unassembled WGS sequence.
DR   GO; GO:0030732; F:methionine S-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-UniRule.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR025779; Met_S-MeTrfase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   PANTHER; PTHR47087; METHIONINE S-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR47087:SF1; METHIONINE S-METHYLTRANSFERASE; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF05175; MTS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 2.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51555; SAM_MT12; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00888};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW   S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU00888};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU00888}.
FT   DOMAIN          247..298
FT                   /note="Methyltransferase small"
FT                   /evidence="ECO:0000259|Pfam:PF05175"
FT   DOMAIN          856..1190
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
SQ   SEQUENCE   1213 AA;  134312 MW;  50B199DC40130273 CRC64;
     MGSAGVEDAA AVAAFLERCA PSGDAAYGEL KAVLGRLHEP TTRRAARVFL TALRPFCSGG
     DSLARYGFRI HDLSLLHCAH DHQFSDRHDN AISPCHGISI ACRPVISNFS SFPHLIHRFI
     RSDSDLTNPM AAAAEVESFL ATCAASGDAA YGAAKAVLER LQDPASRPDA RRLLGAVRRR
     FAGPAAGEEC FRTFHFRIHD VVLDPHLRGF QQRKKLTMME IPSIFIPEDW SFTFYEGLNR
     HPDSIFRDKT VAELGCGNGW ISIALAEKWS PSKVYGLDIN PRAVKIAWIN LYLNALDDDG
     LPIYDGEGKT LLDRVEFYES DLLSYCRDNK IELDRIVGCI PQILNPNPEA MSKIVTENSS
     EEFLYSLSNY CALQGFVEDQ FGLGLIARAV EEGISVIKPM GIMIFNMGGR PGQGVCERLF
     RRRGFRITKL WQTKIMQAAD TDISALVEIE KNSRHRFEFF MDLVGDQPVC ARTAWAYMKS
     GGRISHALSV YSCQLRQPNQ VKKIFEFLKD GFHEVSSSLD LSFDDDSVAD EKIPFLAYLA
     SFLKENKYNP CEPPAGCLNF RNLVAGFMKS YHHIPLTPDN VVVFPSRAVA IENALRLFSP
     ALAIVDEHLT RHLPKQWLTS LAIEGKAKDT VTVIEAPRQS DLLIELIRKL KPQVVVTGMA
     QFEAITSAAF ENLLSVTKDV GSRLFIDISE HLELSSLPSS NGVLKYLAGK TLPSHAAILC
     GLVKNQVYSD LEVAFAISED AAVYRALSQT IELLEGHTSQ ISQHYYGCLF HELLAFQIAD
     RHPQQERLPA EVIPQKMIGF SSSAMSTLKE AEFFIPDSKK SSVIHMDLDR SFLPVPSAVN
     ASIFESFVRQ NITESETDVR SSIQQLVKDS YGFPADGCSE ILYGNTCLAL FNKLALCCIQ
     DQGTLLFPLG ANGHYVSAAK FVNANTLTIP TKLESGFKIE PRVLADTLET VSRPWVYISG
     PTINPTGFLY SDSDIQELLS VCGKYGARVV IDTSFSGLEF QTDGWSRWNL ERCLSAVNCP
     KPSFSVALLG ELSFELTAAG HDFGFLILND SSLVDTFHSF PSLSRPHSTL KYTFKKLLGL
     KNQKDEHFSN LIMEQKDTLK SRADHLIKTL EGCGWDVAGS HGGISMLAKP TAYIGKIIKV
     DGFDGKLDGC NIKEAILRST GLCINSSSWT GIPDHCRFSF ALESSEFERA MGCIVRFKEL
     VLGSKAFHQI NGN
//