ID A0A0E0QD90_ORYRU Unreviewed; 555 AA.
AC A0A0E0QD90;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Nicalin {ECO:0000256|PIRNR:PIRNR011018};
OS Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI08G00180.1, ECO:0000313|Proteomes:UP000008022};
RN [1] {ECO:0000313|Proteomes:UP000008022}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA Zhao Q.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORUFI08G00180.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the nicastrin family.
CC {ECO:0000256|ARBA:ARBA00007717, ECO:0000256|PIRNR:PIRNR011018}.
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DR AlphaFoldDB; A0A0E0QD90; -.
DR SMR; A0A0E0QD90; -.
DR STRING; 4529.A0A0E0QD90; -.
DR EnsemblPlants; ORUFI08G00180.1; ORUFI08G00180.1; ORUFI08G00180.
DR Gramene; ORUFI08G00180.1; ORUFI08G00180.1; ORUFI08G00180.
DR eggNOG; KOG2526; Eukaryota.
DR HOGENOM; CLU_034102_2_0_1; -.
DR OMA; GVKSILH; -.
DR Proteomes; UP000008022; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR CDD; cd03882; M28_nicalin_like; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR016574; Nicalin.
DR PANTHER; PTHR31826; NICALIN; 1.
DR PANTHER; PTHR31826:SF0; NICALIN; 1.
DR Pfam; PF05450; Nicastrin; 1.
DR PIRSF; PIRSF011018; Nicalin; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..555
FT /note="Nicalin"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002371232"
FT TRANSMEM 513..537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 555 AA; 60656 MW; 7B24BB940E36F9A3 CRC64;
MSSSSPSGHL LASVSSALAV LLLLLACVEL GDAAAAVGVY RLIQYDLAGA PLGSRAAALN
HHAAALPLPA AADLSRSALV APLLDLPLAF LRDYLADKKY LGGLLILLPK KLNHEPNNED
KGQVKASLAE LEQLLLHQQV PYPVYFAFQD DHFDNLLADI RKIASSGQPA SATTGGYKLV
VSTPEPRKVA SPTISNIQGW LPGLKGEGET EQLPTIAIVS NYDTFGAAPA LSVGSDSNGS
GAVALLEIAR LFSRLYSNPK TRGKYNLLFG LTSGGPYNYN GTNKWLRSFD QRVRESIDYA
ICLNSVGSWD NELWMHVSKP PENPYIKQIF EDFSDVSKEM GVSVGIKHKK INVSNPRVAW
EHEQFSRFRV TALTLSELSS PPDFLESTGG LYDTRESADA ESVIRTVRLV SESLARHIYG
LKGKNIDVFA ENSSLAINPH YIQSWLDLLS RTPRVAPFLQ KNDPFIAALK KELSEHTADV
HVQSDVLDGM FTFYDATKAT LNVYQVASVT FDLLFLLVIG SYLIILFSFL VITTRGLDDL
INIFRRPPSR KVKGA
//
