ID   A0A0E0QSZ9_ORYRU        Unreviewed;       948 AA.
AC   A0A0E0QSZ9;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=HECT-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012485};
DE            EC=2.3.2.26 {ECO:0000256|ARBA:ARBA00012485};
OS   Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI09G15630.1, ECO:0000313|Proteomes:UP000008022};
RN   [1] {ECO:0000313|Proteomes:UP000008022}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA   Zhao Q.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORUFI09G15630.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.26; Evidence={ECO:0000256|ARBA:ARBA00000885};
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DR   AlphaFoldDB; A0A0E0QSZ9; -.
DR   STRING; 4529.A0A0E0QSZ9; -.
DR   EnsemblPlants; ORUFI09G15630.1; ORUFI09G15630.1; ORUFI09G15630.
DR   Gramene; ORUFI09G15630.1; ORUFI09G15630.1; ORUFI09G15630.
DR   eggNOG; KOG0940; Eukaryota.
DR   HOGENOM; CLU_002173_8_1_1; -.
DR   OMA; CAHRANM; -.
DR   Proteomes; UP000008022; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   CDD; cd00078; HECTc; 1.
DR   Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR   InterPro; IPR000569; HECT_dom.
DR   InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR   InterPro; IPR000626; Ubiquitin-like_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR11254:SF424; E3 UBIQUITIN-PROTEIN LIGASE UPL5; 1.
DR   PANTHER; PTHR11254; HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; 1.
DR   Pfam; PF00632; HECT; 1.
DR   SMART; SM00119; HECTc; 1.
DR   SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50237; HECT; 1.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW   ECO:0000256|PROSITE-ProRule:PRU00104}.
FT   DOMAIN          80..153
FT                   /note="Ubiquitin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50053"
FT   DOMAIN          543..880
FT                   /note="HECT"
FT                   /evidence="ECO:0000259|PROSITE:PS50237"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        847
FT                   /note="Glycyl thioester intermediate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ   SEQUENCE   948 AA;  106236 MW;  C8BC97A9EBE38B18 CRC64;
     MSDADGFGCE HRRPSKRRRD GPDHALLPVS REVLMGHPDD PAAAAAAVGA ESSSASSARG
     VGAPAASASA SAAGGFSCGA HFFVRATDSR TVSMHAAWGD TVGAVLAHLA DRGYGRDLRL
     VYAGRQLAPE TALADLRLPP DSTLHLLSRL RSTPYPDAWQ LASYIASTAA AAKSDPAHTS
     SAANINELVK EFILCAHRAN MRQRHDRDSP LFDAQPTGDH AAQYLEIFRQ AGAPFALVRL
     YAANPSSASH HHAENAIKCF LTMDPSALPP DVLPVMAPVL LEFCGLLSFS VGKRDELYIS
     SRSMLATVLS LPSGLPPCIK SPSKLIEQVL PFAEEIVGVV MDELASLDMT VSSKNLEDLS
     NFFKVLRQQA LRWVPNGGPL PKNLYNSERG HNDTWVWKLH EMSMNLLNRV DECLKRLEMD
     LSLSSENRGV NISQSRWVAR SHMLVMLTQL DFISMIYEDL AHNLRLVLLA HRDPLNALVR
     CSKRNEHLHW LVKHKDLLCF ESRRNLVLMM LPEGKDEYGE LHEMLIDRQH LLDESFEYII
     QARPSELRSG LFMEFKNEEA TGPGVLREWF CMVCQALFSP QQVLFSPCPS DRQRFFLNGT
     SAVDPLHLKY FIFSGRIIGL ALMHRVQVGI TLDRTLFLHL AGRSIKLEDI SAADPVMYAS
     CKRILEMDAA VVDGLELTFS RDVHELGSRR TIELCSGGKD LHVNIRNREL YIDLLIKSTF
     VDSISVQLTH FVRGFSDILV DPELQKVFFE FLDLEDFDGM LGGSNKTINL EDWKLHTQYN
     GYKEKDRQII WFWKAVESLS IEQQRQLLFF WTSVKYLPSD GFGGLASKLY IYKVSESADR
     LPSSHTCFYR LCLPAYPSLK VTRNQLQKIT QEHASIFHIL SGEVWWEHLH RAMLTSSGSQ
     LRLKPCHKVP AGSRNFLGIS QKPVSQQLTS DMDHTLPEHM DSNDVFGI
//