ID A0A0E0QTX2_ORYRU Unreviewed; 532 AA.
AC A0A0E0QTX2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=inositol-1,3,4-trisphosphate 5/6-kinase {ECO:0000256|ARBA:ARBA00012017};
DE EC=2.7.1.159 {ECO:0000256|ARBA:ARBA00012017};
OS Oryza rufipogon (Brownbeard rice) (Asian wild rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4529 {ECO:0000313|EnsemblPlants:ORUFI09G17900.1, ECO:0000313|Proteomes:UP000008022};
RN [1] {ECO:0000313|Proteomes:UP000008022}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. W1943 {ECO:0000313|Proteomes:UP000008022};
RA Zhao Q.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:ORUFI09G17900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol
CC 1,3,4,5-tetrakisphosphate + ADP + H(+); Xref=Rhea:RHEA:13253,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57895,
CC ChEBI:CHEBI:58414, ChEBI:CHEBI:456216; EC=2.7.1.159;
CC Evidence={ECO:0000256|ARBA:ARBA00000680};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol
CC 1,3,4,6-tetrakisphosphate + ADP + H(+); Xref=Rhea:RHEA:20940,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57660,
CC ChEBI:CHEBI:58414, ChEBI:CHEBI:456216; EC=2.7.1.159;
CC Evidence={ECO:0000256|ARBA:ARBA00000399};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-
CC inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+);
CC Xref=Rhea:RHEA:12452, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:57539, ChEBI:CHEBI:57733, ChEBI:CHEBI:456216;
CC EC=2.7.1.134; Evidence={ECO:0000256|ARBA:ARBA00000084};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SIMILARITY: Belongs to the ITPK1 family.
CC {ECO:0000256|ARBA:ARBA00009601}.
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DR AlphaFoldDB; A0A0E0QTX2; -.
DR EnsemblPlants; ORUFI09G17900.1; ORUFI09G17900.1; ORUFI09G17900.
DR Gramene; ORUFI09G17900.1; ORUFI09G17900.1; ORUFI09G17900.
DR Proteomes; UP000008022; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0047325; F:inositol tetrakisphosphate 1-kinase activity; IEA:InterPro.
DR GO; GO:0052726; F:inositol-1,3,4-trisphosphate 5-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0052725; F:inositol-1,3,4-trisphosphate 6-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0032957; P:inositol trisphosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR008656; Inositol_tetrakis-P_1-kinase.
DR InterPro; IPR040464; InsP(3)kin_ATP-grasp.
DR PANTHER; PTHR14217; INOSITOL-TETRAKISPHOSPHATE 1-KINASE; 1.
DR PANTHER; PTHR14217:SF1; INOSITOL-TETRAKISPHOSPHATE 1-KINASE; 1.
DR Pfam; PF05770; Ins134_P3_kin; 1.
DR PIRSF; PIRSF038163; ITPK_uncN; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008022};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 323..508
FT /note="Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp"
FT /evidence="ECO:0000259|Pfam:PF05770"
SQ SEQUENCE 532 AA; 59045 MW; 363115A8DD4B94D3 CRC64;
MPSMRVTTDT WPRRAAQEPL LLLLLRSSLM KSASLQALNP NRAMAAMGRS VRVVLDSSVL
LEPSGVTAEE EEVVVALRPG AEALLRRLRY SNLRVAICHP EGLPTNESGF LEKTAKLYSF
GYMPLTSPSG SNLLNELMLE WSGTNFCFYV TSGVHEGLLS ELQNHNWEVI AMGNEDVIKN
SGVIHISMLQ ELLITLATSI KKEIGNSSAF VRGAFPIYPS KNDLIFVPLS FELPLASQLQ
EVDLVLHKIT DEIINIDPNS SISFPKGISF SPGMSEIIRF VEEHCDFCVI DPFKNIYPLL
DRIQIQEILI RLEGLSAEGR PKLRAPCFLK IESFCGSELQ KQLAEAKLSF PLIVKPQVAC
GVADAHNMAL IFKIEEFSNL SVPLPAILQE YIDHGSKIFK FYAIGDKIFH AIKNSMPNAS
HLKSSSGGKP LTFNSLKTLP VATKEQLLQN EVQDSKLLDI NLVEEAAKLL KELLGLTIFG
FDVVVQESSG DHVIVDLNYL PSFKEVPDNV AMPAFWDAIK QSYESRKQMT QT
//
