ID A0A0E1RYC5_COCIM Unreviewed; 574 AA.
AC A0A0E1RYC5;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Sorting nexin 3 {ECO:0000313|EMBL:EAS35255.2};
GN ORFNames=CIMG_00609 {ECO:0000313|EMBL:EAS35255.2};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS35255.2, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704911; EAS35255.2; -; Genomic_DNA.
DR RefSeq; XP_001246838.2; XM_001246837.2.
DR AlphaFoldDB; A0A0E1RYC5; -.
DR STRING; 246410.A0A0E1RYC5; -.
DR GeneID; 4565351; -.
DR KEGG; cim:CIMG_00609; -.
DR VEuPathDB; FungiDB:CIMG_00609; -.
DR InParanoid; A0A0E1RYC5; -.
DR OMA; YWESFLP; -.
DR OrthoDB; 1891044at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd07627; BAR_Vps5p; 1.
DR CDD; cd06861; PX_Vps5p; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR035803; BAR_Vps5.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR037868; PX_Vps5.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR10555:SF170; FI18122P1; 1.
DR PANTHER; PTHR10555; SORTING NEXIN; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT DOMAIN 164..280
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 452..479
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 12..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 64021 MW; 8D39EDFDA24C1588 CRC64;
MDLEGGDSPW GDVPSQSKSP NNDGSAGKQN DAPSEVALTS PRSPPGRGIR TPRKFGPQVT
RLEAVDGSSD PLGPLGDKSF PPISEQGPVP PQKEPFPARN ARPTSSTSQS SSIAGLMESV
DLEDESETRP RMRPPPPVQP TSSSDDAPKK QIQSSMTVEQ AAKPSFYITV GDPHKVGDLT
SSHIVYQVRT KTTSKAYVRP EFTVTRRYRD FLWLYNSLHN NNPGIVVPPP PEKQAVGRFE
SNFVESRRAA LERMLNKIAA HPVLQHDADL KIFLESDTFN LDVKNKENRE PDLGQSKGMF
SSFGLSVGGG SKFIEHDDWF HDRKIYLEAL ENQLKGLMKA VDTVVQQRKG LAEAASDFAV
SLHSLAGVEL SPALSGPLER LSEVQLRIRE LHERQAQQDV LTLGITIDEY IRLIGSVKTA
FNQRQKSFQS WHSAESDLQK RRNAQDKLLR QGKSQQDRLN QANADVVEAE RKVHQARLLF
EDMGKLMRNE LERFEREKVE DFKSGVETFL ESAVEAQKEL IELWETFFLQ LDADDETNPF
YNPAQTPTSQ PQHERTESGS VSQSTEPTSA QEEA
//
