ID A0A0E3L6J0_9EURY Unreviewed; 411 AA.
AC A0A0E3L6J0;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Cobalt-zinc-cadmium resistance protein {ECO:0000313|EMBL:AKB25106.1};
GN ORFNames=MSMTP_1637 {ECO:0000313|EMBL:AKB25106.1};
OS Methanosarcina sp. MTP4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434100 {ECO:0000313|EMBL:AKB25106.1, ECO:0000313|Proteomes:UP000033049};
RN [1] {ECO:0000313|EMBL:AKB25106.1, ECO:0000313|Proteomes:UP000033049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MTP4 {ECO:0000313|EMBL:AKB25106.1,
RC ECO:0000313|Proteomes:UP000033049};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP009505; AKB25106.1; -; Genomic_DNA.
DR RefSeq; WP_048178707.1; NZ_CP009505.1.
DR AlphaFoldDB; A0A0E3L6J0; -.
DR STRING; 1434100.MSMTP_1637; -.
DR GeneID; 24856969; -.
DR KEGG; metm:MSMTP_1637; -.
DR PATRIC; fig|1434100.4.peg.2172; -.
DR HOGENOM; CLU_013430_3_3_2; -.
DR OrthoDB; 8907at2157; -.
DR Proteomes; UP000033049; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR CDD; cd00851; MTH1175; 1.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR Gene3D; 3.30.70.1350; Cation efflux protein, cytoplasmic domain; 1.
DR Gene3D; 3.30.420.130; Dinitrogenase iron-molybdenum cofactor biosynthesis domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027470; Cation_efflux_CTD.
DR InterPro; IPR036837; Cation_efflux_CTD_sf.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR InterPro; IPR003731; Di-Nase_FeMo-co_biosynth.
DR InterPro; IPR036105; DiNase_FeMo-co_biosyn_sf.
DR InterPro; IPR033913; MTH1175_dom.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR43840; MITOCHONDRIAL METAL TRANSPORTER 1-RELATED; 1.
DR PANTHER; PTHR43840:SF15; MITOCHONDRIAL METAL TRANSPORTER 1-RELATED; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR Pfam; PF02579; Nitro_FeMo-Co; 1.
DR Pfam; PF16916; ZT_dimer; 1.
DR SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
DR SUPFAM; SSF53146; Nitrogenase accessory factor-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033049};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..288
FT /note="Cation efflux protein cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF16916"
FT DOMAIN 307..400
FT /note="Dinitrogenase iron-molybdenum cofactor biosynthesis"
FT /evidence="ECO:0000259|Pfam:PF02579"
SQ SEQUENCE 411 AA; 45212 MW; 5C123A874F9F4167 CRC64;
MVVQENLLLG ANASRNSTFT LVFLAILKGF VGFHSGSSAL IADAVHTSLD IFTSFAVWVG
LKLSLKGNAE KFPYGYYKAD NLVSLFVSVI ILFSGIELVH EALLNIKNPV EIKLQGIALG
TALFSAMSMY ALSQYKARVG RQIDSQALIA DALHSYTDVF SSLIVVIAIA GSILGIMWLD
SVGVLLISLM IFKLGIGIAR DSVLTLMDAW LDRDSITRTR QNVASIQGVK QVEEIRLRKS
GLVVFGEIEI EIEGNADLKR VEMLSEEIEK TVKNEVKNLE HLVINAKPGK MSAMKIAVPV
LEPEGLQSKV SRHFGRAPYF IIFELEGDEI KSWQVNRNPA SGLERKRGLK TAEFLKSQGV
NVVIVGEIGE GPFHNLHDSF VKMLRMPEEA EDVEKVVEKV SGLSRLTSHT E
//
