ID   A0A0E3SRK8_METMT        Unreviewed;      1015 AA.
AC   A0A0E3SRK8;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=CoB--CoM heterodisulfide reductase 2 iron-sulfur subunit D {ECO:0000313|EMBL:AKB85616.1};
DE            EC=1.8.98.1 {ECO:0000313|EMBL:AKB85616.1};
GN   ORFNames=MCMEM_1563 {ECO:0000313|EMBL:AKB85616.1};
OS   Methanococcoides methylutens MM1.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanococcoides.
OX   NCBI_TaxID=1434104 {ECO:0000313|EMBL:AKB85616.1, ECO:0000313|Proteomes:UP000033048};
RN   [1] {ECO:0000313|EMBL:AKB85616.1, ECO:0000313|Proteomes:UP000033048}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MM1 {ECO:0000313|EMBL:AKB85616.1,
RC   ECO:0000313|Proteomes:UP000033048};
RA   Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA   Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT   "Methanogenic archaea and the global carbon cycle.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP009518; AKB85616.1; -; Genomic_DNA.
DR   RefSeq; WP_048205686.1; NZ_CP009518.1.
DR   AlphaFoldDB; A0A0E3SRK8; -.
DR   STRING; 1434104.MCMEM_1563; -.
DR   GeneID; 24894124; -.
DR   KEGG; mmet:MCMEM_1563; -.
DR   PATRIC; fig|1434104.5.peg.1701; -.
DR   HOGENOM; CLU_011400_0_0_2; -.
DR   OrthoDB; 42878at2157; -.
DR   Proteomes; UP000033048; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051912; F:CoB--CoM heterodisulfide reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   PANTHER; PTHR43255:SF1; FERREDOXIN_F(420)H(2)-DEPENDENT COB-COM HETERODISULFIDE REDUCTASE SUBUNIT C; 1.
DR   PANTHER; PTHR43255; IRON-SULFUR-BINDING OXIDOREDUCTASE FADF-RELATED-RELATED; 1.
DR   Pfam; PF02754; CCG; 2.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13534; Fer4_17; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00022485};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW   Oxidoreductase {ECO:0000313|EMBL:AKB85616.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033048}.
FT   DOMAIN          50..220
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
SQ   SEQUENCE   1015 AA;  113129 MW;  267BF013FC83AC9B CRC64;
     MAKNTANLTS SQEEELGGIF GDRVNFSKRE RHFYCHDVGA LPSMAKMMLG NTDPAAIVKL
     RTEDDIVKLM AFARKHSIPV VPRAGASSGY GGVIPTKGGI IADVNLLNDI ISIDAENMTV
     TVGAGIVWER LERKLNEKDL SVCAMPSSAP AATVGGWLVQ NGIGYGSYEY GWSQDTMVSA
     RAVLPNGEVR DFTGSEMDSL IGSMGTVGII TQITLKIRNL EDTASISAEF ADSESLQKAL
     QAVAAEKVPL WSISFINPDW AGMKNEMPFS THHGEPVVED RPELPKSYIC NFIYPESRDV
     SALENIITSN GGKILSEEIS KHEAGEWFRS MKVKRLGPSF IPAEIIVPVD KVGKVFNEIK
     AKVDLPVLIE GMVEKNGNVI LLCFIPHSER SFKFNLAFTL GISIIKIAEE NGGRIYASGL
     YFAKEAEKVY GDRLKKMLAL KQQVDPDDIM NPETISGKGI LKAGISMSKA FEPIMRFVGN
     RSGVGEETFR KQKDIPADIV SHAYTCAQCG YCVEECDQYY GRGWESQSPR GKWFFIKEYL
     AGRDKMTQEQ VDTFLACTTC ELCDHRCQLD LPINDSWMTM REELVVERGM MTIPPFEIMA
     SSLLKERNIW GEYLKNREEW MPEDLKPKIK DKAEYAYFAG CTASFVEKDI AEASVRLLTD
     AGMEITYLGK EESCCGIPML AAGKWDVFEK IMRMNIENMR KKGVKTVITS CPACWLVWDT
     FYRQWAEKLG IEYDFEAKHY SQVLQDKLDV LSEKFVEPLD RVVTVHDACH MGRAGGIYEP
     PRDLIKAVPG VELREMEHNR AEGHCCGSVL TLVADPDVAG VVGNMRLKEA EDIGADIMVA
     ACPCCQVQLR IAAEKSGSPV DVQDLSATVA RSMGYDIPDT TNAALTAWIT FDQMIHLLKP
     ENMTDLMVEL LPQMMAAMPA PLRGMMKMVK YVPGMDLMMK PMMPVMMPML LPGIMPKVMP
     DMLEAVGRRV QMSDDLREQM PDLMPKSMEN LMPNMLPQII PLLTPRMIEY IKTEF
//