ID A0A0E3UHH7_9BACT Unreviewed; 497 AA.
AC A0A0E3UHH7;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:AKC81705.1};
GN ORFNames=IMCC26134_00975 {ECO:0000313|EMBL:AKC81705.1};
OS Verrucomicrobia bacterium IMCC26134.
OC Bacteria; Verrucomicrobiota.
OX NCBI_TaxID=1637999 {ECO:0000313|EMBL:AKC81705.1, ECO:0000313|Proteomes:UP000033046};
RN [1] {ECO:0000313|EMBL:AKC81705.1, ECO:0000313|Proteomes:UP000033046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC26134 {ECO:0000313|EMBL:AKC81705.1,
RC ECO:0000313|Proteomes:UP000033046};
RA Choi A., Kang I., Cho J.-C.;
RT "Complete genome sequence of Verrucomicrobia strain IMCC26134.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; CP011265; AKC81705.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0E3UHH7; -.
DR STRING; 1637999.IMCC26134_00975; -.
DR KEGG; vba:IMCC26134_00975; -.
DR PATRIC; fig|1637999.3.peg.206; -.
DR HOGENOM; CLU_019748_3_0_0; -.
DR OrthoDB; 9801795at2; -.
DR Proteomes; UP000033046; Chromosome.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AKC81705.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033046}.
FT DOMAIN 8..212
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 317..461
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 286
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 356
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 376
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 380
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 400
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 497 AA; 53827 MW; 19A014192E9DA704 CRC64;
MPHPFPIINA QEAAALIHHG NTVAFGGFTP SGSPKDIPTA IAGRAMAEHA AGRPFQIGVI
TGASTGASLD GALAKAEAIS FRTPYQSDPD LRRAINAGKT RFFDLHLSQL PQHVRTGALG
PIHWTVLEAC DITADGRVVL TSGVGAAPTF ARCGERILIE LNQRHPASLC GIHDIYEPID
PPYRGEIPLY NVSDRIGQPW LQLDPAKIAG VVLTNREDEI GAFAEPDAVT TKIGENVADF
LAAELRAGRI PPEFLPLQSG VGDIANAVLG ALGAHPEIPR FTMYSEVLQD ATLALLRSGK
LKFASGCSLT LSPPAMRSLY EDLSALRGRI VLRPQEITNN PEIVRRIGII SVNTAIEADL
QGNINSTHLF GKTMMNGIGG SGDFTRNAHL SIFTCPSLQK SGKISTIVPQ VTHTDHSEHS
VQVIVTEHGV ADLRRLDPFQ RAELIIERCA HPDFRADLRR YLALSRDGHE PFNFDYAFAF
HQRFNKTGDM RGVVWPG
//
