ID A0A0E3X0G9_METMT Unreviewed; 406 AA.
AC A0A0E3X0G9;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Pyruvate:ferredoxin oxidoreductase, alpha subunit {ECO:0000313|EMBL:AKB85290.1};
DE EC=1.2.7.1 {ECO:0000313|EMBL:AKB85290.1};
GN ORFNames=MCMEM_1237 {ECO:0000313|EMBL:AKB85290.1};
OS Methanococcoides methylutens MM1.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanococcoides.
OX NCBI_TaxID=1434104 {ECO:0000313|EMBL:AKB85290.1, ECO:0000313|Proteomes:UP000033048};
RN [1] {ECO:0000313|EMBL:AKB85290.1, ECO:0000313|Proteomes:UP000033048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM1 {ECO:0000313|EMBL:AKB85290.1,
RC ECO:0000313|Proteomes:UP000033048};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC chain. {ECO:0000256|ARBA:ARBA00011595}.
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DR EMBL; CP009518; AKB85290.1; -; Genomic_DNA.
DR RefSeq; WP_048205405.1; NZ_CP009518.1.
DR AlphaFoldDB; A0A0E3X0G9; -.
DR STRING; 1434104.MCMEM_1237; -.
DR GeneID; 24893780; -.
DR KEGG; mmet:MCMEM_1237; -.
DR PATRIC; fig|1434104.5.peg.1355; -.
DR HOGENOM; CLU_002569_5_0_2; -.
DR OrthoDB; 372068at2157; -.
DR Proteomes; UP000033048; Chromosome.
DR GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:AKB85290.1};
KW Pyruvate {ECO:0000313|EMBL:AKB85290.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033048}.
FT DOMAIN 16..239
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 262..364
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 406 AA; 45104 MW; F2245EDDFF78A2D2 CRC64;
MAKEMLTGNA AAAWGVRLAE VDYIPAYPIT PQTEIIETIA KWISDGEMDA GFVTMDSEHS
MVTAAGAASA TGARTFTTTS SQGLMYGFEM LFTVAGWRVP LVMVNVSRGL SAPITLGPDH
NDILALRDTG FLQIHCETCQ EVLDSVLMAY RLAEDDRVLL PLMVNMDGFF LSFTREAVEV
PDVEKVRSFL PEYQPEHAFF RAGQPMAQGV AVLGGEFYSY FKYQMHLASQ NALEVYREVS
DDFERIFGRK YGTIDEYMME DAEYVLVMTN SFSTLGKAAV KRARENGIKA GLLRPRFLRP
FPEADIRNAL KGKKAVAVID QNISVGKGGI IYSEMASCLY NENSRPLMLS FIGGLGGKNI
SQEEFDLIFE KMIHAEDSGI VGLPHLLYTK KEWEGIKKLK EIAGRQ
//
