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Database: UniProt
Entry: A0A0E3YSJ5_9BACT
LinkDB: A0A0E3YSJ5_9BACT
Original site: A0A0E3YSJ5_9BACT 
ID   A0A0E3YSJ5_9BACT        Unreviewed;       457 AA.
AC   A0A0E3YSJ5;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   05-JUL-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=IMCC26134_00005 {ECO:0000313|EMBL:AKC81559.1};
OS   Verrucomicrobia bacterium IMCC26134.
OC   Bacteria; Verrucomicrobia; unclassified Verrucomicrobia.
OX   NCBI_TaxID=1637999 {ECO:0000313|EMBL:AKC81559.1, ECO:0000313|Proteomes:UP000033046};
RN   [1] {ECO:0000313|EMBL:AKC81559.1, ECO:0000313|Proteomes:UP000033046}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMCC26134 {ECO:0000313|EMBL:AKC81559.1,
RC   ECO:0000313|Proteomes:UP000033046};
RA   Choi A., Kang I., Cho J.-C.;
RT   "Complete genome sequence of Verrucomicrobia strain IMCC26134.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP011265; AKC81559.1; -; Genomic_DNA.
DR   RefSeq; WP_046296950.1; NZ_CP011265.1.
DR   EnsemblBacteria; AKC81559; AKC81559; IMCC26134_00005.
DR   KEGG; vba:IMCC26134_00005; -.
DR   PATRIC; fig|1637999.3.peg.1; -.
DR   KO; K02313; -.
DR   Proteomes; UP000033046; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000033046};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033046}.
FT   DOMAIN      152    281       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      364    434       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     160    167       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   457 AA;  51365 MW;  C2D455B2F9FD6320 CRC64;
     MLVTSVSPGL WESAKADLRG LFPEDVFKLW FDPIVCVEAT PEQMTLGVPN DFAAIWINDN
     YIDLIQQRLR LTSGREMAVK LRKIAADSSA GTLLSTPRPR PAAPRRVIRV EDRPIQNSSL
     NPRNTFETFV VGDNNQMAAA AARAVADAPG QSYNPLFLYG ETGLGKTHLM HAIGHAVLQR
     RPDTRVAYLS AEKFTNDFIQ AIQENGLIKF RQRYRHVDVL LIDDIQFLAG KERSQEEFFH
     TFNDLHGTGK QIVISSDRRA SEIEKLEARL VSRFEWGLPA DIQPPDFETR LAILRTKAAA
     MKCDLPAPIA AFIAQHISRN IRRLEGALLK VASHTQLTGK PLDLPAVEML LKDVLMEQAQ
     NQLTLEVIQK RVADHFQIRY SDMTSKRRPN NIAIPRQIAM YLTRTLIAKH SLQDIGDAFG
     GRDHGTVIHA CKAVDNMIAQ DAHMRGQIEF LRNALSR
//
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