ID   A0A0F0HP64_9PSEU        Unreviewed;       347 AA.
AC   A0A0F0HP64;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=IMP dehydrogenase {ECO:0000313|EMBL:KJK57280.1};
GN   ORFNames=UK12_17545 {ECO:0000313|EMBL:KJK57280.1};
OS   Saccharothrix sp. ST-888.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharothrix.
OX   NCBI_TaxID=1427391 {ECO:0000313|EMBL:KJK57280.1, ECO:0000313|Proteomes:UP000033409};
RN   [1] {ECO:0000313|EMBL:KJK57280.1, ECO:0000313|Proteomes:UP000033409}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ST-888 {ECO:0000313|EMBL:KJK57280.1,
RC   ECO:0000313|Proteomes:UP000033409};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.;
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJK57280.1}.
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DR   EMBL; JYJF01000050; KJK57280.1; -; Genomic_DNA.
DR   RefSeq; WP_045303948.1; NZ_JYJF01000050.1.
DR   AlphaFoldDB; A0A0F0HP64; -.
DR   PATRIC; fig|1427391.3.peg.5213; -.
DR   OrthoDB; 241504at2; -.
DR   Proteomes; UP000033409; Unassembled WGS sequence.
DR   CDD; cd08287; FDH_like_ADH3; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033409};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          26..129
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          180..306
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   347 AA;  35799 MW;  56919A35525D04E6 CRC64;
     MRATVIHGPN DIRIEEVPDP RIQWPTDAVV RVVNACICGS DLWAYRGVAA REAGQRIGHE
     FLGIVEEVGS EVSGFKPGDF VVAPFVWSDG TCDFCREGLH TSCPEGGFWG EVGSDGGQGE
     AVRVPFADGT LVQLPKEAAG DQKLLPGLLA LSDVMSTGHH AAVSAGVRPG ATVAVVGDGA
     VGLCGVLAAH RLGAGRVIAL GRHQVRTDIA RKFGATDVVA ERGEAAIEAV KELTGGQGAH
     AVLEAVGTEE SMRTAISIAR DGGAVGYVGV PHGGSAGVDI GQMFGRNVSL NGGVAPARAY
     IPELLPDVLS GAIDPGLVFD RTVDLAGVPD GYRAMDNRSA LKVRIGF
//